Ahmet GİRGEÇ, Fatih TEMİZ, Sadık YURTTUTAN, Zübeyde DİNÇER, Osman Nuri ÖZEN, Can ACIPAYAM

Hiperkalsemi ve Çoklu Patolojik Kemik Fraktürü ile Başvuran Akut Lenfoblastik Lösemi

Hiperkalsemi, bazı lenfoproliferatif hastalıklarda sıkça görülmesine rağmen çocukluk çağı akut lenfoblastik lösemilerinde nadir bir komplikasyondur. Bu yazıda hiperkalsemi ve çoğul patolojik kemik kırıkları ile başvuran ve akut lösemi tanısı konulan 8 yaşında bir erkek olgu sunulmuştur. Hiperkalsemi etkeni olabilecek tüm nedenler araştırıldı ve laboratuar testler normal bulundu. Hiperkalsemi, intravenöz izotonik sodyum klorür, furosemid, steroidler ve bifosfonatlar ile tedavi edildi. Hiperkalsemi, çocukluk çağı akut lenfoblastik löseminin başlangıç laboratuvar bulgusu olabilir. Tekrarlayan laboratuvar ve periferik yayma incelemeleri hiperkalseminin ayırıcı tanısında önemlidir.

Anahtar Kelimeler:

akut lenfoblastik lösemi, hiperkalsemi

Hiperkalsemi ve Çoklu Patolojik Kemik Fraktürü ile Başvuran Akut Lenfoblastik Lösemi

Hypercalcemia is common in some lymphoproliferative disorders, but is a rare complication of acute lymphoblastic leukemia in childhood. We report a 8-year-old boy who presented with hypercalcemia and multiple pathologic bone fracture was diagnosed to have acute lymphoblastic leukemia. All the disorders that could be the reason of hypercalcemia and the laboratory tests were within normal limits. Hypercalcemia was treated with intravenous isotonic sodium chloride solution, furosemide and biphosphonates. Hypercalcemia may be a presenting laboratory finding of acute lymphoblastic leukemia in childhood. Repeat laboratory and peripheral blood smear examinations are important for differential diagnosis of hypercalcemia.

Keywords:

akut lenfoblastik lösemi, hiperkalsemi,

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