Çağrı GÜLTEKİN, Gökhan ULUKAN, Gökay YEŞİLOVALI, Süleyman ÖZDEMİR, Mehmet Ege İNCE, F. Eser ÖZGENCİL

Treatment of a Full-Thickness Skin Wound in Gluteal Region of the Vervet Monkey with Topical Insulin

In a female vervet monkey brought to our hospital with the complaint of anaphylactic shock depending on snake bite, a gangrenous wound was detected in right gluteal region and traditional local cicatrizing and epithelizing pomade application and systemic treatment were performed for 10 days. As no signs of epithelization and shrinkiage was observed during this treatment, a new treatment protocol was started with topical insulin pomade. It was determined that epithelization started on the 4th days and completely recovered on the 46th days of the treatment and 30 days after the completion of topical insulin treatment the wound region was became hairy. It was concluded that topical treatment with insulin pomade had positive effects on delayed secondary wound healing in vervet monkeys whom their cutaneous trunci muscle (M. panniculus carnosus) responsible for wound contraction was not functional.

Bir Vervet Maymununun Gluteal Bölgesindeki Maddi Kayıplı Deri Yarasının Topikal İnsülin İle Sağaltımı

Hastanemize yılan ısırığına bağlı anaflaktik şok şikayeti ile getirilen dişi vervet maymununda, sağ gluteal bölgede gangrenli deri yarası tespit edildikten sonra 10 gün boyunca geleneksel lokal sikatrizan ve epitelizan pomat uygulamaları ve sistemik sağaltım yapıldı. Yarada epitelizasyon ve küçülmenin hiç gözlenmemesi üzerine topikal insulin pomat uygulamasına geçildi. Uygulamanın 4. gününde epitelizasyonun başladığı, 46. günde tamamlandığı, topikal insulin sağaltımının kesilmesinden sonra 30. günde ise epitelizasyon bölgesinin tüylendiği gözlendi. Sonuç olarak, yaranın kontraksiyonla küçülmesini sağlayan cutaneous trunci (M. panniculus carnosus) kasının non-human primatlarda fonksiyonel olmadığı, topikal insülin pomat uygulamalarının gecikmiş sekunder yara iyileşmesinde pozitif katkıları olduğu gözlendi.

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