Murat YÜKSEL, Onur BAŞBUĞ, İbrahim YURDAKUL

Sığırların Bazı İnflamatuar Hastalıklarında Serum Amiloid A ve Prokalsitoninin Değerlendirilmesi

İnsanlarda ve hayvanlarda yapılan son çalışmalar, enfeksiyöz hastalıkları daha doğru ve etkili şekilde teşhis edebilmek için serum amiloid A (SAA) ve prokalsitonin (PCT) gibi infamasyon biyobeliteçlerine odaklanmıştır. Bu çalışmanın amacı, inflamatuar hastalığı olan sığırların tanısında SAA ve PCT seviyelerinin değerlendirilmesidir. On sağlıklı kontrol sığır ve sistemik inflamatuar yanıt sendromlu (SIRS) 64 hasta sığır dahil edildi. Sığırlarda inflamatuar hastalık klinik olarak şüpheli vakalarda, klinik bulgular ve laboratuvar incelemelerine dayanarak teşhis edildi. SAA ve PCT konsantrasyonları, sığırlar için ticari bir ELISA ile ölçüldü. Enflamatuar hastalığı olan sığırlarda SAA ve PCT konsantrasyonları sağlıklı kontrollerden anlamlı olarak daha yüksekti (sırasıyla, P

Evaluation of Serum Amyloid A and Procalcitonin in Some Inflammatory Diseases of Cattle

Recent study in humans and animals has been focused on inflammatory biomarkers that infectious diseases, such as serum amyloid A (SAA),procalcitonin (PCT), that may more accurately and efficiently diagnose inflammation. The aim of this study was to evaluate SAA and PCTlevels in the diagnosis of cattle with inflammatory disease. Ten healthy control cattle and 64 patients with systemic inflammatory responsesyndrome (SIRS) were included in cattle. Inflammatory disease in cattle was diagnosed based on clinical signs and the laboratory examinationin clinically suspected cases. SAA and PCT concentrations were measured with a commercial ELISA assay for cattle. SAA and PCT concentrationsin cattle with inflammatory disease were significantly higher than in the healthy controls (respectively, P

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