KADİR BOZUKLUHAN, Emine ATAKİŞİ, Onur ATAKiŞİ

Nitric oxide levels, total antioxidant and oxidant capacity in cattle with foot-and-mouth-disease

Çalışmanın amacı şap hastalığına (FMD) yakalanmış sığırlarda total antioksidan (TAC), oksidan kapasite (TOC) ve nitrik oksit (NO) seviyelerini araştırmaktır. Araştırmada, yaşları 24 ve 48 ay arasında olan 20 Montofon ırkı sığır kullanıldı. Hayvanlar kontrol (n=10) ve şap hastalıklı (n=10) olmak üzere iki gruba ayrıldı. Kan örnekleri Vena jugularis’ ten alınarak santrifuj edildi. Şaplı hayvanlarda TOC ve NO seviyeleri kontrol grubundaki hayvanlara göre önemli düzeyde yüksekti. TAC seviyesinde ise şap hastalıklı ve kontrol grubu arasında önemli bir değişiklik saptanmadı. Sonuç olarak şap hastalığının sığırlarda serum NO ve TOC seviyesini artırırken, TAC seviyesini etkilemediği belirlendi.

Anahtar Kelimeler:

süt sığırı, antioksidanlar, kan kimyası, sığır, sığır hastalıkları, şap hastalığı, nitrik oksit, oksitleyiciler, viral hastalıklar

Şap hastalıklı sığırlarda nitrik oksit düzeyi, total antioksidan ve oksidan kapasite

The aim of this study was to investigate total antioxidant (TAC), oxidant capacity (TOC) and nitric oxide levels (NO) in cattle with foot-and-mouth-diseases (FMD). Twenty Swiss Brown cattle aged between 24 and 48 months were used. Animals were divided into two groups as control (n=10) and FMD (n=10). Blood samples were collected from jugular vein and centrifuged. TOC and NO levels were found to be significantly higher in FMD group compared to those of control group. However, no significant differences were present in TAC levels between FMD and control groups. It was concluded that FMD increases serum NO levels and TOC, but do not affect TAC in cattle.

Keywords:

dairy cattle, antioxidants, blood chemistry, cattle, cattle diseases, foot and mouth disease, nitric oxide, oxidants, viral diseases,

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