Marko PAJIĆ, Nevenka ALEKSIĆ, Branislav VEJNOVIĆ, Vladimir POLAČEK, Nikolina NOVAKOV, Dušica Ostojić ANDRIĆ, Zoran STANIMIROVIC

Inflence of Anticoccidials on Oxidative Stress, Production Performance and Faecal Oocyst Counts in Broiler Chickens Infected with Eimeria Species

The inflence of certain anticoccidial drugs on oxidative stress in broiler chickens infected with Eimeria species was assessed. There were two untreated (uninfected and infected), and three groups infected and treated with anticoccidials. The first treated group (Ro) was given robenidine, the 2nd a herbal anticoccidial (Herb) and the 3 rd the combination of robenidine and the herbal anticoccidial (Ro+Herb). All infected groups were on day 14 challenged with oral inoculation of oocysts. The activities of catalase (CAT), superoxide dismutase (SOD) and glutathione S-transferase (GST), and the concentration of malondialdehyde (MDA) were estimated in blood taken on days 21 and 40. The oocyst numbers were calculated per gram, and chicken body weight and feed conversion ratio (FCR) measured. The activities of CAT, GST and the level of MDA were significantly lower (P

Antikoksidiyal Maddelerin Eimeria Türleri İle Enfekte Etlik Piliçlerde Oksidatif Stres, Üretim Performansı ve Dışkı Oosit Sayıları Üzerine Etkisi

Eimeria türleri ile enfekte Broilerlerde bazı antikoksidiyal ilaçların oksidatif stress üzerine etkisi araştırılmıştır. Çalışmada, enfekte edilmeyen ve enfekte edilen olmak üzere iki, ayrıca enfekte edilerek uygulama yapılan üç grup vardı. Uygulama yapılan gruplardan ilkine robenidin (Ro), ikincisine bitkisel antikoksidiyal (Herb) ve üçüncüsüne robenidin ile birlikte bitkisel antikoksidiyal (Ro+Herb) uygulandı. Tüm enfekte edilen gruplara 14. günde oral oosit inookulasyonu yapıldı. Çalışmanın 21 ve 40. günlerinde alınan kan örneklerinde katalaz (CAT), süperoksit dismutaz (SOD) ve glutatyon S-transferaz (GST) aktiviteleri ile malondialdehit (MDA) konsantrasyonu incelendi. Her bir gramdaki oosit sayıları hesaplandı ve tavukların vücut ağırlıkları ile yem konversiyon oranları ölçüldü. Uygulama yapılmayan grupla karşılaştırıldığında antikoksidiyal uygulanan gruplarda CAT, GST aktivitileri ve MDA seviyeleri anlamlı olarak daha düşük (P

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