Hamid MUSTAFA, Waqas Ahmad KHAN, Kim EUISOO, Zulfiqar Hussain KUTHU, Adeela AJMAL, Afzal ALI, Khalid JAVED, Tad S. SONSTEGARD

Genetic Properties of Copy Number Variations in Some Pakistani Cattle Breeds

A copy number variation (CNV) is information of DNA segment containing deletion, duplication or insertion exist within diverse populations. This study detected 53 CNVs regions that overlapped with immune response, body size and parasitic resistance traits in Pakistani cattle breeds. This study characterized genetic diversity and provides lineage differentiated CNVs in these indigenous cattle breeds. Keywords: Copy number variation, Diversity, Traits, Breed, Pakistan

Pakistan’da Bazı Sığır Irklarında Kopya Sayısı Değişikliklerinin Genetik Özellikleri

Kopya sayısı değişikliği (CNV) farklı popülasyonlar içerisinde delesyon, duplikasyon ve insersiyonları içeren DNA segmentlerinin bilgisidir. Bu çalışma ile Pakistan sığır ırkları arasında bağışıklık yanıtı, vücut boyutu ve parazit direnci özelliklerini içeren 53 CNV tespit edildi. Bu çalışma; belirtilen yerel sığır ırkları arasında genetik çeşitliliği göstermiş ve hat farklı CNV’leri belirlemiştir.

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