Nasir RAJPUT, Sher ALI, Rana Muhammad BILAL, Wang TIAN

Eimeria İle Enfekte Edilmiş Etlik Piliçlerde Bitki Kökenli Karotenoidleri (Curcumin ve Lutein) İçeren Diyet Takviyesinin Enfeksiyonun Kontrolündeki Rolü

Doğal olarak oluşan bitki kökenli karotenoidlerin (kurkumin ve lutein), Eimeria verilmiş etlik piliçlerde anti-koksidiyal etkinliği test edildi. Toplam 200 adet bir günlük ticari Arbor Acres civcivine 42 gün boyunca bakım uygulandı. Civcivler tek tek tartıldı ve 5 tekrarlı olmak üzere rastgele 4 eşit sağaltım grubuna ayrıldı. Kontrol grubu T0’a ait civcivler, ek besin içermeyen temel bir diyetle beslendi. T1, T 2 ve T 3 grubundaki civcivlere, her bir kg yem içerisinde sırasıyla 300 mg/kg kurkumin, 300 mg/kg lutein ve 150 mg kurkumin artı 150 mg lutein içeren diyet uygulandı. 21. günde tüm civcivlere Eimeria maxima verildi. Çalışma bulguları, tüm gruplar arasında yem tüketimi, canlı ağırlık artışı ve yemden yararlanmanın istatistiksel olarak değişmediğini ortaya koydu (P>0.05). Lutein takviyeli diyetlerle beslenen piliçlere kıyasla, T0 grubunda karaciğer ve dalak ağırlıklarında anlamlı derecede (P

Role of Dietary Supplementation with Plant Origin Carotenoids (Curcumin and Lutein) for the Control of Eimeria-Challenged Broiler Chickens

The infl uence of anti-coccidial naturally occurring plant origin carotenoids (curcumin and lutein) in Eimeria-challenged broiler chicks were tested. A total of 200, day-old commercial Arbor Acres chicks were reared for 42 days. The chicks were weighed individually and randomly assigned into equally 4 treatment groups having 5 replicates. Chicks of control group T0 were raised on a basal diet with no supplement. The chicks of group T 1, T 2 and T 3 were supplemented with curcumin 300 mg/kg, lutein 300 mg/kg, and curcumin plus lutein 150 mg each with per kg of feed, respectively. On day 21 all the chicks were challenged with Eimeria maxima. The findings of this study revealed that among all the groups feed intake, body weight gain and feed efficiency remained statistically unchanged (P>0.05). A significantly higher (P

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1. Soutter F, Werling D, Tomley FM, Blake DP: Poultry coccidiosis: Design and interpretation of vaccine studies. Front Vet Sci, 7:101, 2020. DOI: 10.3389/fvets.2020.00101
2. Blake DP, Knox J, Dehaeck B, Huntington B, Rathinam T, Ravipati V, Ayoade S, Gilbert W, Adebambo AO, Jatau ID, Raman M, Parker D, Rushton J, Tomley FM: Re-calculating the cost of coccidiosis in chickens. Vet Res, 51 (1): 1-14, 2020. DOI: 10.1186/s13567-020-00837-2
3. Zhang K, Li X, Na C, Abbas A, Abbas RZ, Zaman MA: Anticoccidial effects of Camellia sinensis (green tea) extract and its effect on blood and serum chemistry of broiler chickens. Pak Vet J, 40, 77-80, 2020. DOI: 10.29261/pakvetj/2020.015
4. Kim WH, Lillehoj HS: Immunity, immunomodulation, and antibiotic alternatives to maximize the genetic potential of poultry for growth and disease response. Anim Feed Sci Technol, 250, 41-50, 2019. DOI: 10.1016/j. anifeedsci.2018.09.016
5. Rajput N, Naeem M, Ali S, Rui Y, Tian W: Effect of dietary supplementation of marigold pigment (lutein) on immunity, skin and meat color, and growth performance of broiler chickens. Braz J Poult Sci, 14 (4): 233-304, 2012. DOI: 10.1590/S1516-635X2012000400009
6. Rajput N, Muhammad N, Yan R, Zhong X, Wang T: Effect of dietary supplementation of curcumin on growth performance, intestinal morphology and nutrients utilization of broiler chicks. J Poult Sci, 50, 44- 52, 2013. DOI: 10.2141/jpsa.0120065
7. Rajput N, Naeem M, Ali S, Zhang JF, Zhang L, Wang T: The effect of dietary supplementation with the natural carotenoids curcumin and lutein on broiler pigmentation and immunity. Poult Sci, 92, 1177-1185, 2013. DOI: 10.3382/ps.2012-02853
8. Nogareda C, Moreno JA, Angulo, E, Sandmann G, Portero M, Capell T, Zhu C, Christou P: Carotenoid‐enriched transgenic corn delivers bioavailable carotenoids to poultry and protects them against coccidiosis. Plant Biotechnol J, 14 (1): 160-168, 2016. DOI: 10.1111/pbi.12369
9. NRC: National Research Council. Nutrient Requirements of Poultry. 9 th revised ed., National Academy Press. Washington, USA. 1994. DOI: 10.17226/2114
10. Michels MG, Bertolini LCT, Esteves AF, Moreira P, Franca SC: Anticoccidial effects of coumestans from Eclipta alba for sustainable control of Eimeria tenella parasitosis in poultry production. Vet Parasitol, 177, 55-60, 2011. DOI: 10.1016/j.vetpar.2010.11.022
11. Ogbe AO, Atawodi SE, Abdu PA, Sannusi A, Itodo AE: Changes in weight gain, faecal oocyst count and packed cell volume of Eimeria tenella-infected broilers treated with a wild mushroom (Ganoderma lucidum) aqueous extract. J S Afr Vet Assoc, 80, 97-102, 2009. DOI: 10.4102/ jsava.v80i2.179
12. Youn HJ, Noh JW: Screening of the anticoccidial effects of herb extracts against Eimeria tenella. Vet Parasitol, 9 (4): 257-263, 2001. DOI: 10.1016/s0304-4017(01)00385-5
13. Johnson J, Reid WM: Anticoccidial drugs: Lesion scoring techniques in battery and floor-pen experiments with chickens. Exp Parasitol, 28, 30- 36, 1970. DOI: 10.1016/0014-4894(70)90063-9
14. Zhang XH, Zhong X, Zhou YM, Du HM, Wang T: Effect of RRR-α- tocopherol succinate on the growth and immunity in broilers. Poult Sci, 88, 959-966, 2009. DOI: 10.3382/ps.2008-00512
15. Partovi R, Saeed S, Pabast M, Mohajer A, Sadighara P: Effect of dietary supplementation of nano curcumin on oxidant stability of broiler chicken meat infected with Eimeria species. Vet Res Forum, 11 (2): 159-163, 2020. DOI: 10.30466/vrf.2018.86733.2125
16. Allen PC, Danforth HD, Augustine PC: Dietary modulation of avian coccidiosis. Int J Parasitol, 28, 1131-1140, 1998. DOI: 10.1016/s0020- 7519(98)00029-0
17. Lee SH, Lillehoj HS, Lillehoj EP, Cho SM, Park DW, Hong YH, Chun HK, Park HJ: Immunomodulatory properties of dietary plum on coccidiosis. Comp Immunol Microbiol Infect Dis, 3, 389-402, 2008. DOI: 10.1016/j.cimid.2007.06.005
18. Durrani FR, Ismail M, Sultan A, Suhail SM, Chand N, Durrani Z: Effect of different levels of feed added turmeric (Curcuma longa) on the performance of broiler chicks. Am J Agric Biol Sci, 1, 9-11, 2006.
19. Allen PC, Fetterer RH: Recent advances in biology and immuno- biology of Eimeria species and in diagnosis and control of infection with these coccidian parasites of poultry. Clin Microbiol Rev, 15, 58-65, 2002. DOI: 10.1128/CMR.15.1.58-65.2002
20. Moryani AA, Rajput N, Naeem M, Shah AH, Jahejo AR: Screening of the herbs and evaluation of their combined effects on the health and immunity of coccidiosis challenged broiler chickens. Pak Vet J, 41 (2): 228- 234, 2021. DOI: 10.29261/pakvetj/2021.005
21. Ntrallou K, Gika H, Tsochatzis E: Analytical and sample preparation techniques for the determination of food colorants in food matrices. Foods, 9(1):58, 2020. DOI: 10.3390/foods9010058
22. Karadas F, Erdogan S, Kor D, Ot G, Uluman M: The effects of different types of antioxidants (Se, vitamin E and carotenoids) in broiler diets on the growth performance, skin pigmentation and liver and plasma antioxidant concentrations. Braz J Poult Sci, 18 (1): 101-116, 2016. DOI: 10.1590/18069061-2015-0155
23. Abolfathi AA, Daryoush M, Ali R, Mehrdad N: Green tea attenuates hepatic tissue injury in STZ-streptozotocin-induced diabetic rats. J Anim Vet Adv, 11, 2081-2090, 2012. DOI: 10.3923/javaa.2012.2081.2090
24. Navaei-Nigjeh M, Rahimifard M, Pourkhalili N, Nili-Ahmadabadi A, Pakzad M, Baeeri M, Abdollahi M: Multi-organ protective effects of cerium oxide nanoparticle/selenium in diabetic rats: Evidence for more efficiency of nanocerium in comparison to metal form of cerium. Asian J Anim Vet Adv, 7, 605-612, 2012. DOI: 10.3923/ajava.2012.605.612
25. Zamora R, Hidalgo FJ, Tappel AL: Comparative antioxidant effectiveness of dietary β-carotene, vitamin E, selenium and coenzyme Q10 in rat erythrocytes and plasma. J Nutr, 121, 50-56, 1991. DOI: 10.1093/ jn/121.1.50
26. Cheng YH, Shen TF, Pang VF, Chen BJ: Effects of aflatoxin and carotenoids on growth performance and immune response in mule ducklings. Comp Biochem Physiol C Toxicol Pharmacol, 128, 19-26, 2001. DOI: 10.1016/s1532-0456(00)00173-3
27. Zhai SS, Ruan D, Zhu YW, Li MC, Ye H, Wang WC, Yang L: Protective effect of curcumin on ochratoxin A-induced liver oxidative injury in duck is mediated by modulating lipid metabolism and the intestinal microbiota. Poult Sci, 99 (2): 1124-1134, 2020. DOI: 10.1016/j.psj.2019.10.041