The aim of the study was to evaluate effects of presence or absence of a dominant follicle (DF) estimated by a single ultrasound examination at the time of follicular aspiration (FA) on superstimulatory and superovulatory responses and embryo production in lactating Simmental cows. At random stages of the estrous cycle, the ovaries of cows (n=42) were examined by transrectal ultrasonography (US) and all follicles ≥3 mm were counted. Donors with
Bu çalışmanın amacı, laktasyondaki Simental ineklerde follikül aspirasyonu (FA) zamanında tek bir ultrason muayenesi ile saptanan dominant follikül (DF) varlığı veya yokluğunun süperstimülatör ve süperovulatör cevaplar ve embriyo üretimi üzerindeki etkilerinin değerlendirilmesiydi. Östrus siklusunun tesadüfi aşamalarında, ineklerin (n=42) ovaryumları ultrason (US) ile muayene edilerek ≥3 mm tüm folliküller sayıldı. Üç-8 mm çapında
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1. Surjus RS, Prata AB, Borsato M, Mattos FCSZ, Martins da Silveira MC, Mourao GB, Pires AV, Wiltbank MC, Sartori R: In vivo embryo production in cows superovulated 1 or 2 days after ovum pick-up. Reprod Fertil Dev, 26 (4): 527-532, 2014. DOI: 10.1071/RD12398
2. Bó GA, Guerrero DC, Adams GP: Alternative approaches to setting up donor cows for superstimulation. Theriogenology, 69 (1): 81-87, 2008. DOI: 10.1016/j. theriogenology.2007.09.005
3. Lima WM, Vieira AD, Thaller Neto A, Mezzalira A, Matos RC, Gregory RM: Improved superovulatory response in beef cattle following ovarian follicular ablation using a simplified transvaginal device. Anim Reprod Sci, 100, 364-370, 2007. DOI: 10.1016/j.anireprosci.2006.10.023
4. Bungartz L, Niemann H: Assessment of the presence of a dominant follicle and selection of dairy cows suitable for superovulation by a single ultrasound examination. J Reprod Fertil, 101, 583-591, 1994. DOI: 10.1530/jrf.0.1010583
5. Singh J, Dominguez M, Jaiswal R, Adams GP: A simple ultrasound test to predict superovulatory response in cattle. Theriogenology, 62, 227-243, 2004. DOI: 10.1016/j.theriogenology.2003.09.020
6. İleri İK, Sayın T: Sığırlarda embriyo transfer çalışmaları. J Fac Vet Univ Istanbul, 12 (1): 23-35, 1986.
7. Mikkola M, Taponen J: Embryo yield in dairy cattle after superovulation with Folltropin or Pluset. Theriogenology, 88, 84-88, 2017. DOI: 10.1016/j. theriogenology.2016.09.052
8. Galli C, Duchi R, Crotti G, Turini P, Ponderato N, Colleoni S, Lagutina I, Lazzari G: Bovine embryo technologies. Theriogenology, 59 (2): 599-616, 2003. DOI: 10.1016/S0093-691X(02)01243-8
9. Kawamata M: Relationships between the number of small follicles prior to superovulatory treatment and superovulatory response in Holstein cows. J Vet Med Sci, 56 (5): 965-967, 1994. DOI: 10.1292/jvms.56.965
10. Dias FCF, Dadarwal D, Adams GP, Mrigank H, Mapletoft RJ, Singh J: Length of the follicular growing phase and oocyte competence in beef heifers. Theriogenology, 79 (8): 1177-1183, 2013. DOI: 10.1016/j.theriogenology.2013.02.016
11. Palomino JM, Cervantes MP, Mapletoft RJ, Woodbury MR, Adams GP: Effect of extending FSH treatment on superovulation and embryo production in wood bison (Bison bison athabascae). Theriogenology, 95, 18-23, 2017. DOI: 10.1016/j. theriogenology.2017.02.020
12. Pancarcı ŞM, Ari UC, Atakisi O, Güngör Ö, Çiğremiş Y, Bollwein H: Nitric oxide concentrations, estradiol-17β progesterone ratio in follicular fluid, and COC quality with respect to perifollicular blood flow in cows. Anim Reprod Sci, 130 (1-2): 9-15, 2012. DOI: 10.1016/j.anireprosci. 2011.12.013
13. Cirit Ü, Özmen MF, Küçükaslan İ, Köse M, Kutsal HG, Çınar EM: Effect of the interval from follicle aspiration to initiation of lengthened FSH treatment on follicular superstimulatory and superovulatory responses and embryo production in lactating simmental cows. Theriogenology, 128, 218-224, 2019. DOI: 10.1016/j. theriogenology.2019.02.008
14. Karaşahin T, Akyol N, Satılmış M, Kızıl SH, Bucak MN, Çoyan K: Investigation of conception rates achieved with the transfer of sexed and unsexed bovine embryos. Turk J Vet Anim Sci, 38, 253-256, 2014. DOI: 10.3906/vet-1310-22
15. Bülbül B, Kırbaş M, Köse M, Dursun Ş: Investigation of superovulation response in Brown Swiss cows after synchronization using progesterone and oestradiol valerate. Kafkas Univ Vet Fak Derg, 16 (3): 463-468, 2010. DOI: 10.9775/ kvfd.2009.1024
16. Stringfellow DA, Givens MD: Manual of the International Embryo Transfer Society. 1-170, Illinois: Savoy, 2010.
17. García Guerra A, Tribulo A, Yapura J, Singh J, Mapletoft RJ: Lengthening the superstimulatory treatment protocol increases ovarian response and number of transferable embryos in beef cows. Theriogenology, 78 (2): 353-360, 2012. DOI: 10.1016/j.theriogenology.2012.02.010
18. Souza AH, Carvalho PD, Rozner AE, Vieira LM, Hackbart KS, Bender RW, Dresch AR, Verstegen JP, Shaver RD, Wiltbank MC: Relationship between circulating anti-Müllerian hormone (AMH) and superovulatory response of highproducing dairy cows. J Dairy Sci, 98 (1): 169-178, 2015. DOI: 10.3168/jds.2014-8182
19. Dias FCF, Costa E, Adams GP, Mapletoft RJ, Kastelic J, Dochi O, Singh J: Effect of duration of the growing phase of ovulatory follicles on oocyte competence in superstimulated cattle. Reprod Fertil Dev, 25 (3): 523-530, 2013. DOI: 10.1071/ RD11284
20. Cevik M, Kocyigit A, Sen U, Kuran M: Can sequential human embryo culture media be used in bovine in vitro embryo culture. Kafkas Univ Vet Fak Derg, 20 (1): 149-153, 2014. DOI: 10.9775/kvfd.2013.9676
21. Enginler SÖ, Özdaş ÖB, Sandal Aİ, Arıcı R, Ertürk E, Baran A, Toydemir TFS, Tek Ç, Kılıçarslan MR, Ak K: The effect of cysteamine and oviductal cells in different culture media on the development of sheep embryos. Kafkas Univ Vet FakDerg, 22 (1): 139-145, 2016. DOI: 10.9775/kvfd.2015.14115
22. Evecen M, Demir K, Arıcı R, Yağcıoğlu S, Ersoy N, Coşkun N, Armutak E, Üvez A, Gürel Gürevin E, Eser A, Atalla H, Ak K, Pabuccuoğlu S, Birler S: Effects of ovary transport and storage temperature on in vitro maturation and cumulus cell apoptosis rates in cat oocytes. Kafkas Univ Vet Fak Derg, 24 (2): 301-306, 2018. DOI: 10.9775/kvfd.2017.18880
23. Akyol N, Ertem TB, Varışlı Ö: Investigation of the effects of storage period for frozen bull semen on in vitro embryo production. Kafkas Univ Vet Fak Derg, 25 (2): 257-262, 2019. DOI: 10.9775/kvfd.2018.20839
24. Ireland JJ, Ward F, Jimenez-Krassel F, Ireland JLH, Smith GW, Lonergan P, Evans ACO: Follicle numbers are highly repeatable within individual animals but are inversely correlated with FSH concentrations and the proportion of goodquality embryos after ovarian stimulation in cattle. Hum Reprod, 22 (6): 1687-1695, 2007. DOI: 10.1093/humrep/dem071
25. Kohram H, Moakhar HK: Relationship between follicular profiles prior to the initiation of superovulation and various types of superovulatory responses in cattle. Bull Vet Inst Pulawy, 54, 29-33, 2010.
26. Shaw DW, Farin PF, Washburn SP, Britt JH: Effect of retinol palmitate on ovulation rate and embryo quality in superovulated cattle. Theriogenology, 44 (1): 51-58, 1995. DOI: 10.1016/0093-691X(95)00147-Z
27. Demetrio D: AETA 2017 Survey Report. https://www.aeta.org/docs/ 2017_ Stats.pdf; Accessed: 08.10.2018.
28. Donaldson LE: Cattle breed as a source of variation in embryo transfer. Theriogenology, 21 (6): 1013-1018, 1984. DOI: 10.1016/0093-691X(84)90396-0
29. Tríbulo A, Rogan D, Tríbulo H, Tríbulo R, Mapletoft RJ, Bó GA: Superovulation of beef cattle with a split-single intramuscular administration of Folltropin-V in two concentrations of hyaluronan. Theriogenology, 77 (8): 1679-1685, 2012. DOI: 10.1016/j.theriogenology. 2011.12.013
30. Kanitz W, Becker F, Schneider F, Kanitz E, Leiding C, Nohner HP, Pöhland R: Superovulation in cattle: Practical aspects of gonadotropin treatment and insemination. Reprod Nutr Dev, 42 (6): 587-599, 2002. DOI: 10.1051/rnd:2002045
31. Martens G, Nohner HP, Leiding C, Schneider F, Becker F, Nuernberg G, Kanitz W: Optimizing frequency of FSH application for superovulatory treatment in cattle. Reprod Fertil Dev, 17 (2): 313-314, 2005. DOI: 10.1071/RDv17n2Ab326
32. Carballo Guerrero D, Tríbulo A, Tríbulo R, Tríbulo H, Bó GA: Superovulatory response in beef cattle treated during the first follicular wave following synchronization of ovulation with a progestin device and GnRH. Reprod Fertil Dev, 21 (1): 242-243, 2009. DOI: 10.1071/RDv21n1Ab291
33. Bono G, Gabai G, Silvestrelli L, Comin A: Superovulatory and endocrinological responses of Simmental cows treated either with PMSG or hMG or in combination. Theriogenology, 35 (6): 1179-1190, 1991. DOI: 10.1016/0093-691X(91)90364-J
34. Breuel KF, Baker RD, Butcher RL, Townsend EC, Inskeep EK, Dailey RA, Lerner SP: Effects of breed, age of donor and dosage of follicle stimulating hormone on the superovulatory response of beef cows. Theriogenology, 36 (2): 241-255, 1991. DOI: 10.1016/0093-691X(91)90383-O
35. Stroud B: AETA 2009 Survey Report. https://www.aeta.org/docs/ 09statsreport. pdf; Accessed: 08.10.2018.
36. Roussel JD, Thibocieaux JK, Karihallo AK, Goodeaux LL: A seven-year study of embryo transfer donors. PAS, 7 (1): 8-12, 1991. DOI: 10.15232/S1080- 7446(15)32169-0
37. Leonardi CEP, Pfeifer LFM, Rubina MIB, Singh J, Mapletoft RJ, Pessoa GA, Bainy AM, Silva CAM: Prostaglandin F2α promotes ovulation in prepubertal heifers. Theriogenology, 78 (7): 1578-1582, 2012. DOI: 10.1016/j.theriogenology. 2012.06.030
38. Ambrose DJ, Gobikrushanth M, Zuidhof S, Kastelic JP: Low-dose natural prostaglandin F2α (dinoprost) at timed insemination improves conception rate in dairy cattle. Theriogenology, 83 (4): 529-534, 2015. DOI: 10.1016/j.theriogenology. 2014.10.034