Mükremin ÖLMEZ, TARKAN ŞAHİN, Mustafa MAKAV, Özlem KARADAĞOĞLU

Effect of Resveratrol Supplemented to Japanese Quail (Coturnix coturnix japonica) Rations on Performance and Some Biochemical Parameters

This experiment was conducted to evaluate the changes on growth performance, carcass and some biochemical parameters of Japanese quail fed supplemental Resveratrol (Res). A total of 200 quails were distributed at equal body weights into four experimental groups, each consisting of five replicate pens having ten birds/replicate pen: 1- basal diet without Res (Control), 2- basal diet + 100 mg/kg Res, 3- basal diet + 200 mg/kg Res, and 4- basal diet + 400 mg/kg Res. There were no significant effects of the supplementation of resveratrol on body weight gain and carcass traits (P>0.05). Inclusion of Res in quail rations improved feed consumption (P

Japon Bıldırcın (Coturnix coturnix japonica) Rasyonlarına İlave Edilen Resveratrol’ün Performans ve Bazı Biyokimyasal Parametreler Üzerine Etkisi

Bu çalışmada Japon bıldırcın rasyonlarına ilave edilen resveratrolün (Res) büyüme aktivitesi ile ilişkisinin belirlenmesi amaçlandı. Çalışmada eşit canlı ağırlığa sahip 200 adet bıldırcın civcivi beşer tekrarlı (10 civciv) olacak şekilde ve her grupta 50 adet hayvan bulunan dört deneme grubuna ayrıldı. Resveratrolün Japon bıldırcınlarında performans, karkas özellikleri, serum antioksidan ve bazı biyokimyasal parametreleri üzerine etkisini belirlemek için 1- Res içermeyen bazal diyet (Kontrol), 2- bazal diyet + 100 mg/kg Res, 3- bazal diyet + 200 mg/kg Res ve 4- bazal diyet + 400 mg/kg Res gruplarına ayrıldı. Resveratrol ilavesinin canlı ağırlık artışı ve karkas parametrelerini etkilemediği belirlendi (P>0.05). Japon bıldırcın rasyonlarına Res ilavesi ile 3-5 haftalık periyotta ve çalışmanın tamamında (0-5 hafta) yem tüketimi ve yem dönüşüm oranı önemli derecede etkilendi (P0.05). Sonuç olarak, elde edilen bulgulara göre Res’in bıldırcın rasyonlarında 400 mg/kg’a kadar büyüme destekleyici bir katkı maddesi olarak güvenle kullanılabileceği kanaati oluşmuştur.

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1. Islam KMS, Schuhmacher A, Gropp JM: Humic acid substances in animal agriculture. Pakistan J Nutr, 4 (3): 126-134, 2005. DOI: 10.3923/ pjn.2005.126.134

2. Mutuş R, Kocabağlı N, Alp M, Acar N, Eren M, Gezen ŞŞ: The effect of dietary probiotic supplementation on tibial bone characteristics and strength in broilers. Poult Sci, 85 (9): 1621-1625, 2006. DOI: 10.1093/ ps/85.9.1621

3. Kucukersan S, Kucukersan K, Colpan I, Goncuoglu E, Reisli Z, Yesilbag D: The effects of humic acid on egg production and egg traits of laying hen. Vet Med (Praha), 50 (9): 406-410, 2005. DOI: 10.17221/5640-VETMED

4. Trckova M, Zraly Z, Bejcek P, Matlova L, Beran V, Horvathova A, Faldyna M, Moravkova M, Shitaye JE, Svobodova J, Pavlık I: Effect of feeding treated peat as a supplement to newborn piglets on the growth, health status and occurrence of conditionally pathogenic mycobacteria. Vet Med (Praha), 51 (12): 544-554, 2006. DOI: 10.17221/5589-VETMED

5. Yörük MA, Gül M, Hayirli A, Macit M: The effects of supplementation of humate and probiotic on egg production and quality parameters during the late laying period in hens. Poult Sci, 83 (1): 84-88, 2004. DOI: 10.1093/ps/83.1.84

6. Şahin T, Elmalı DA, Kaya İ, Sarı M, Kaya Ö: The Effect of single and combined use of probiotic and humate in quail (Coturnix coturnix japonica) diet on fatttening performance and carcass parameters. Kafkas Univ Vet Fak Derg, 17 (1): 1-5, 2011. DOI: 10.9775/kvfd.2010.640

7. Cetin I, Yesilbag D, Cengiz SS, Belenli D: Effects of supplementation with rosemary (Rosmarinus officinalis L.) volatile oil on growth performance, meat MDA level and selected plasma antioxidant parameters in quail diets. Kafkas Univ Vet Fak Derg, 23 (2): 283-288, 2017. DOI: 10.9775/ kvfd.2016.16438

8. Baur JA, Sinclair DA: Therapeutic potential of resveratrol: The in vivo evidence. Nat Rev Drug Discov, 5 (6): 493-506, 2006. DOI: 10.1038/nrd2060

9. Zhang Z, Gao L, Cheng Y, Jiang J, Chen Y, Jiang H, Yu H, Shan A, Cheng B: Resveratrol, a natural antioxidant, has a protective effect on liver injury induced by inorganic arsenic exposure. Biomed Res Int, 2014: 617202, 2014. DOI: 10.1155/2014/617202

10. Zhu W, Chen S, Li Z, Zhao X, Li W, Sun Y, Zhang Z, Ling W, Feng X: Effects and mechanisms of resveratrol on the amelioration of oxidative stress and hepatic steatosis in KKAy mice. Nutr Metab, 11:35, 2014. DOI: 10.1186/1743-7075-11-35

11. Ling K, Wan MLY, El-Nezami H, Wang M: Protective capacity of resveratrol, a natural polyphenolic compound, against deoxynivalenolinduced intestinal barrier dysfunction and bacterial translocation. Chem Res Toxicol, 29 (5): 823-833, 2016. DOI: 10.1021/acs.chemrestox.6b00001

12. Alagawany MM, Farag MR, Dhama K, Abd El-Hack ME, Tiwari R, Alam GM: Mechanisms and beneficial applications of resveratrol as feed additive in animal and poultry nutrition: A review. Int J Pharmacol, 11 (3): 213-221, 2015. DOI: 10.3923/ijp.2015.213.221

13. Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, Kalra A, Prabhu VV, Allard JS, Lopez-Lluch G, Lewis K, Pistell PJ, Poosala S, Becker, Boss O, Gwinn D, Wang M, Ramaswamy S, Fishbein KW, Spencer RG, Lakatta EG, le Couteur D, Shaw RJ, Navas P, Puigserver P, Ingram DK, de Cabo R, Sinclair DA: Resveratrol improves health and survival of mice on a high-calorie diet. Nature, 444 (7117): 337-342, 2006. DOI: 10.1038/nature05354

14. Ölmez M, Makav M, Eroğlu HA, Şahin T: Kanatlı beslemede doğal bir yem katkı kaynağı: Resveratrol. Kafkas Üniv Fen Bil Enst Derg, 10 (2): 238-244, 2017.

15. Timmers S, Konings E, Bilet L, Houtkooper RH, van de Weijer T, Goossens GH, Hoeks J, van der Krieken S, Ryu D, Kersten S, MoonenKornips E, Hesselink MKC, Kunz I, Schrauwen-Hinderling VB, Blaak EE, Auwerx J, Schrauwen P: Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. Cell Metab, 14 (5): 612-622, 2011. DOI: 10.1016/j. cmet.2011.10.002

16. Akosman MS, Demirel HH, Turkmen R: Protective effect of resveratrol on kidney and liver histopathology induced by NMDA receptor antagonist Mk-801 in mice. Kafkas Univ Vet Fak Derg, 26 (1): 83-87, 2020. DOI: 10.9775/ kvfd.2019.22370

17. Yan Y, Yang JY, Mou YH, Wang LH, Zhou YN, Wu CF: Differences in the activities of resveratrol and ascorbic acid in protection of ethanolinduced oxidative DNA damage in human peripheral lymphocytes. Food Chem Toxicol, 50 (2): 168-174, 2012. DOI: 10.1016/j.fct.2011.10.046

18. Liu LL, He JH, Xie HB, Yang YS, Li JC, Zou Y: Resveratrol induces antioxidant and heat shock protein mRNA expression in response to heat stress in black-boned chickens. Poult Sci, 93 (1): 54-62, 2014. DOI: 10.3382/ ps.2013-03423

19. Rubiolo JA, Vega FV: Resveratrol protects primary rat hepatocytes against necrosis induced by reactive oxygen species. Biomed Pharmacother, 62 (9): 606-612, 2008. DOI: 10.1016/j.biopha.2008.06.034

20. Wiciński M, Socha M, Walczak M, Wódkiewicz E, Malinowski B, Rewerski S, Górski K, Pawlak-Osińska K: Beneficial effects of resveratrol administration-focus on potential biochemical mechanisms in cardiovascular conditions. Nutrients, 10 (11): 1813, 2018. DOI: 10.3390/ nu10111813

21. Dyck GJ, Raj P, Zieroth S, Dyck JR, Ezekowitz JA: The effects of resveratrol in patients with cardiovascular disease and heart failure: A narrative review. Int J Mol Sci, 20 (4): 904, 2019. DOI: 10.3390/ijms20040904

22. Sridhar M, Suganthi RU, Thammaiah V: Effect of dietary resveratrol in ameliorating aflatoxin B1-induced changes in broiler birds. J Anim Physiol Anim Nutr, 99, 1094-1104, 2015. DOI: 10.1111/jpn.12260

23. Karadağoğlu Ö, Şahin T, Ölmez M, Yakan A, Özsoy B: Changes in serum biochemical and lipid profile, and fatty acid composition of breast meat of broiler chickens fed supplemental grape seed extract. Turk J Vet Anim Sci, 44 (2): 182-190, 2020. DOI: 10.3906/vet-1906-37

24. Mohebodini H, Jazi V, Bakhshalinejad R, Shabani A, Ashayerizadeh A: Effect of dietary resveratrol supplementation on growth performance, immune response, serum biochemical indices, cecal microflora, and intestinal morphology of broiler chickens challenged with Escherichia coli. Livest Sci, 229, 13-21, 2019. DOI: 10.1016/j.livsci.2019.09.008

25. NRC: Nutrient Requirements of Poultry: 1994. 9th rev. ed., National Academy Press, Washington, DC, 1994.

26. Jones R: A standard method for the dissection of poultry for carcass analysis. The West of Scotland Agricultural College, Auchincruive Ayr, Technical note, 222, 1984.

27. He S, Li S, Arowolo MA, Yu Q, Chen F, Hu R, He J: Effect of resveratrol on growth performance, rectal temperature and serum parameters of yellow‐feather broilers under heat stress. Anim Sci J, 90 (3): 401-411, 2019. DOI: 10.1111/asj.13161

28. Zhang C, Zhao X, Wang L, Yang L, Chen X, Geng Z: Resveratrol beneficially affects meat quality of heat-stressed broilers which is associated with changes in muscle antioxidant status. Anim Sci J, 88 (10): 1569-1574, 2017. DOI: 10.1111/asj.12812

29. Dal-Pan A, Blanc S, Aujard F: Resveratrol suppresses body mass gain in a seasonal non-human primate model of obesity. BMC Physiol, 10:11, 2010. DOI: 10.1186/1472-6793-10-11

30. Ahmed ST, Hossain ME, Kim GM, Hwang JA, Ji H, Yang CJ: Effects of resveratrol and essential oils on growth performance, immunity, digestibility and fecal microbial shedding in challenged piglets. Asian Australas J Anim Sci, 26 (5): 683-690, 2013. DOI: 10.5713/ajas.2012.12683

31. Kim D, Hong E, Ji S, Lee W, Bang H, Kang H, Kim H, Kim S: Effects of dietary resveratrol on growth performance, blood biochemical parameter, immunoglobulin, and blood antioxidant activity in broiler chicks. Korean J Poult Sci, 42 (2): 147-156, 2015. DOI: 10.5536/KJPS.2015.42.2.147

32. Abdel-Wahab AA, Abdel-Kader I, Ahmad EM: Effect of dietary grape seed supplementation as a natural growth promoter on the growth performance of japanese quail. Egyptian J Nutr Feeds, 21 (2): 537-548, 2018. DOI: 10.21608/ejnf.2018.75746

33.Xia N, Daiber A, Förstermann U, Li H: Antioxidant effects of resveratrol in the cardiovascular system. Br J Pharmacol, 174 (12): 1633-1646, 2017. DOI: 10.1111/bph.13492

34. Sahin K, Akdemir F, Orhan C, Tuzcu M, Hayirli A, Sahin N: Effects of dietary resveratrol supplementation on egg production and antioxidant status. Poult Sci, 89 (6): 1190-1198, 2010. DOI: 10.3382/ps.2010-00635

35. Bredt DS, Snyder SH: Nitric oxide: A physiologic messenger molecule. Annu Rev Biochem, 63 (1): 175-195, 1994. DOI: 10.1146/annurev. bi.63.070194.001135