BÜLENT ÖZSOY, Zafer CANTEKİN, Sakine YALÇIN, Hamdullah Suphi BAYRAKTAR

Eff ects of Kefir on Blood Parameters and Intestinal Microfl ora in Rats: An Experimental Study

A probiotic product of kefir is widely consumed by human beings. The purpose of this research was to investigate the eff ects of kefir on blood parameters and intestinal fl ora in rats. A total of 24 female rats were used in this study. During 35 days of experimental period, rats were fed with a commercial diet and water was provided ad libitum. Kefir was given at the levels of 10 mL/kg, 20 ml/kg and 30 mL/kg with oral gavage to the first, second and third treatment groups, respectively. Kefir was not given to the control group. The number of yeast was found to be 1.65x107 and the number of lactobacilli was found to be 4x108 in kefir. At the end of the experiment, blood samples were taken from all rats. Blood plasma parameters and were investigated. The intestinal microfl ora was investigated by classical colony counting method. No diff erences were observed among the groups in total protein, albumin, uric acids, SGPT, SGOT, alkaline phosphatase and phosphorus in blood plasma. The plasma triglyceride and cholesterol levels in the second and third groups were lower than control group (P

Ratlarda Kefirin Bağırsak Mikrofl orası ve Bazı Kan Parametrelerindeki Rolü: Deneysel Çalışma

Probiyotik bir ürün olan kefir insanlar tarafından yaygın olarak tüketilmektedir. Bu araştırmanın amacı, kefirin ratlarda kan parametreleri ve bağırsak fl orası üzerindeki etkilerini araştırmaktır. Bu çalışmada toplam 24 dişi rat kullanıldı. Otuzbeş günlük deney süresi boyunca, ratlar ticari rat yemi ile beslendi ve su ad libitum verldi. Kefir, deneme gruplarına sırası ile 10, 20 ve 30 mL/kg seviyelerinde oral gavajla verildi. Kontrol grubuna kefir verilmedi. Kefir maya sayısı 1.65x107 lactobacilli sayısı 4x108 bulunmuştur. Kan plazmasındaki total protein, albümin, ürik asit, SGPT, SGOT, alkalin fosfataz ve fosfor açısından gruplar arasında fark gözlenmedi. İkinci ve üçüncü gruptaki plazma trigliserid ve kolesterol, seviyeleri kontrol grubuna göre daha düşüktü (P

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