ÖZGÜR ÖZDEMİR, MEHMET BURAK ATEŞ, Mustafa ORTATATLI, Funda TERZİ, Tülay AVCI, Fatih HATİPOĞLU, Mustafa Kemal ÇİFTÇİ

Dog Massacre with Pesticide for Theft: Methomyl Poisoning

In this case report, acute methomyl poisoning in dogs is described by pathological and toxicological findings for the first time in Turkey. Five of the thirty stray dogs that were found dead within 1-2 days after eating the foodstuffs in an industrial area in Konya were necropsied. Grossly, undigested pieces of chicken meat with a mild insecticidal smell in stomach of all dogs were found and toxicological analysis by GC-MS revealed toxic levels of methomyl in the stomach contents (15.7-17.8 ppm) and, intestines, livers and kidneys (1.2-2.9 ppm) also. In addition, histopathologically degenerative and necrotic changes were observed in liver, brain, lung, kidneys and gastrointestinal system mucosa. Postmortem and histopathological examinations and toxicological analyses revealed that deaths were related to methomyl poisoning and it has been subsequently learned from the police officers and printed media that this poison had been deliberately infected to dog food for the purpose of theft committed in the industrial area. Publishing these intentional poisoning events, we have wanted to draw attention to that more serious measures and statutory regulations should be taken by governments about animal rights.

Hırsızlık İçin Tarım İlacıyla Köpek Katliamı: Metomil Zehirlenmesi

Bu olgu sunumunda, Türkiye’de ilk kez köpeklerde akut metomil zehirlenmesi patolojik ve toksikolojik bulgularıyla tanımlanmıştır. Konya’daki bir sanayi bölgesinde, yemlerini yedikten sonraki 1-2 gün içerisinde ölü olarak bulunan 30 adet sokak köpeğinden 5 tanesine nekropsi yapılmıştır. Nekropside köpeklerin midelerinde hafif insektisit kokusu içeren sindirilmemiş tavuk parçalarına rastlanılmış olup, GC-MS cihazıyla yapılan toksikolojik analiz sonucu mide içeriğinde (15,7-17.8 ppm) ve ayrıca bağırsaklar, karaciğer ve böbreklerde (1.2-2.9 ppm) toksik düzeyde metomil tespit edilmiştir. Ayrıca histopatolojik olarak karaciğer, beyin, akciğer, kalp, böbrek ve gastrointestinal sistem mukozalarında dejeneratif değişikler gözlenmiştir. Postmortem ve histopatolojik bulgular ile toksikolojik analizler neticesinde ölümlerin metomil zehirlenmesine bağlı olarak şekillendiği ortaya konulmuş olup, daha sonra adli makamlar ile yazılı basından alınan bilgilerden bu zehirin köpek yiyeceklerine bölgede gerçekleştirilen hırsızlık amacıyla kasten bulaştırıldığı öğrenilmiştir. Bu kasıtlı zehirlenme vakası ile, hükümetler tarafından hayvan hakları konusunda daha ciddi ve yasal önlemlerin alınması gerektiğine dikkat çekilmek istenilmiştir.

PDF

___

1. Van Scoy AR, Yue M, Deng X, Tjeerdema RS: Environmental fate and toxicology of methomyl. Rev Environ Contam Toxicol, 222, 93-109, 2013. DOI: 10.1007/978-1-4614-4717-7_3

2. Vale A, Lotti M: Organophosphorus and carbamate insecticide poisoning. In, Lotti M, Bleecker ML (Eds): Handbook of Clinical Neurologyed., 149-168, Elsevier, 2015. DOI: 10.1016/B978-0-444-62627-1.00010-X

3. Yurdakök-Dikmen B, Tekin K, Tırpan MB, Daşkın A, Filazi A: In vitro toxicity of some pesticides on goat and dog spermatozoa. Kafkas Univ Vet Fak Derg, 23 (2): 297-303, 2017. DOI: 10.9775/kvfd.2016.16501

4. Hamzah DJ, Abo-Ktifa MA, Rasheed SS, Faris BH: Toxopathological study of methamyl effect on the Rock Pigeons (Culumba Livia Gaddi). Bas J Vet Res, 14 (1): 124-134, 2015.

5. WHO: The WHO recommended classification of pesticides by hazard and guidelines to classification 2009. 2009. https://www.who.int/ipcs/ publications/pesticides_hazard_2009.pdf; Accessed: 07.12.2018.

6. Caloni F, Cortinovis C, Rivolta M, Davanzo F: Animal poisoning in Italy: 10 years of epidemiological data from the Poison Control Centre of Milan. Vet Rec, 170 (16): 415, 2012. DOI: 10.1136/vr.100210

7. Kaplan AM, Sherman H: Toxicity studies with methyl N-[[(methylamino) carbonyl]oxy]-ethanimidothioate. Toxicol Appl Pharmacol, 40 (1): 1-17, 1977. DOI: 10.1016/0041-008X(77)90110-7

8. Hopper K, Aldrich J, Haskins SC: The recognition and treatment of the intermediate syndrome of organophosphate poisoning in a dog. J Vet Emerg Crit Car, 12 (2): 99-103, 2002. DOI: 10.1046/j.1435-6935.2002.00008.x

9. Albo AG, Nebbia C: Incidence of poisonings in domestic carnivores in Italy. Vet Res Commun, 28 (Suppl. 1): 83-88, 2004. DOI: 10.1023/b:ve rc.0000045383.84386.77

10. FAO/WHO: Pesticide residues in food report of the 2001 joint FAO/ WHO meeting of experts.2001.http://www.fao.org/fileadmin/templates/ agphome/documents/Pests_Pesticides/JMPR/Reports_1991-2006/ REPORT2001.pdf; Accessed: 07.12.2018.

11. Caloni F, Cortinovis C, Rivolta M, Davanzo F: Suspected poisoning of domestic animals by pesticides. Sci Total Environ, 539, 331-336, 2016. DOI: 10.1016/j.scitotenv.2015.09.005

12. Martinez-Haro M, Mateo R, Guitart R, Soler-Rodriguez F, Perez- Lopez M, Maria-Mojica P, Garcia-Fernandez AJ: Relationship of the toxicity of pesticide formulations and their commercial restrictions with the frequency of animal poisonings. Ecotoxicol Environ Saf, 69 (3): 396-402, 2008. DOI: 10.1016/j.ecoenv.2007.05.006

13. Radad K, Hashim A, El-Sharqawy EEG, El-Din Youssef MS: Histopathological effects of methomyl on sprague-dawley rats after repeated application. Bulg J Vet Med, 12 (2): 149-157, 2009.

14. Radad K, Mostafa AH, Youssef MS: Neuropathologic effects of methomyl on sprague-dawley rats. Assiut Vet Med J, 55 (123): 180-190, 2009.

15. Gjurovski I, Dovenska M, Janevski A, Ristoski T: Poisoning of dogs in the Republic of Macedonia - Pathomorphological changes and the impact on animal welfare. Mac Vet Rev, 41 (2): 203-207, 2018. DOI: 10.2478/ macvetrev-2018-0014