YILDIRAY BAŞBUĞAN, ZAHİD TEVFİK AĞAOĞLU, Nazmi YÜKSEK

An investigation on serum troponin concentration in healthy ruminants

Bu çalışmada sağlıklı ruminantlarda kardiak troponinlerin (cTn I ve cTn T) düzeylerinin belirlenmesi amaçlandı. Çalışmanın materyalini klinik olarak sağlıklı 30 sığır (15 erkek, 15 dişi), 30 Akkaraman koyun (15 erkek, 15 dişi) ve 30 keçi (15 erkek, 15 dişi) oluşturdu. Her üç türdeki hayvanlar 0-6 aylık, 6-12 aylık ve 12 ay ve üzeri olmak üzere gruplara ayrıldı. Vena jugularisten usulüne uygun olarak alınan ve elde edilen serum örneklerinden kardiak troponin I ve T düzeyleri ve biyokimyasal parametreler (CK, CK-MB, AST ve LDH) ölçüldü. Troponin T değerleri her üç türde negatif (-) olarak belirlendi. Troponin I sığırlarda 0-0.23 ng/ml (ortalama 0.18 ng/ml), koyunlarda 0-0.21 ng/ml (ortalama 0.15 ng/ml) ve keçilerde de 0-0.24 ng/ml (ortalama 0.20 ng/ml) değerleri arasında olduğu, cinsiyet ve yaş açısından da üç türde de belirtilen sınırlarda olduğu tespit edildi. CK, CK-MB, AST ve LDH seviyelerinin normal sınırlar arasında olmasına rağmen AST sığır ve koyunlarda 0-6 aylıklarda, LDH koyun ve keçilerde 6-12 aylıklarda yüksek olduğu belirlendi. Sonuç olarak bu çalışma sağlıklı ruminantlar için serum troponin değerlerini teşkil edebileceği kanısına varıldı.

Anahtar Kelimeler:

kan serumu, troponin, koyun, geviş getiren hayvanlar, laktat dehidrogenaz, kalp, keçi, kreatin kinaz, sığır, kan kimyası, aspartat aminotransferaz

Sağlıklı ruminantlarda serum troponin düzeylerinin araştırılması

The present study aimed to investigate the cardiac troponin (cTn I and cTn T) levels in healthy ruminants. The study involved 30 cattle (15 male, 15 female), 30 Akkaraman sheep (15 male, 15 female) and 30 goats (15 male, 15 female) and all animals were clinically healthy. The study animals were grouped as 0-6 months, 6-12 months and 12 months and over. Blood samples were obtained from jugular vein and cardiac troponin I and T levels, and biochemical parameters (CK, CK-MB, AST and LDH) were measured. Troponin T values were found as negative in all three species. Troponin I values were 0-0.23 ng/ml (mean 0.18 ng/ml) in cattle, 0-0.21 ng/ml (mean 0.15 ng/ml) in sheep and 0-0.24 ng/ml (mean 0.20 ng/ml) in goats. It was also found that the values were in declared limits for cattle and sheep. Although CK, CK-MB, AST and LDH values were in normal ranges AST levels were higher in cattle and sheep of 0-6 months of age and, LDH levels were higher in sheep and goat at 6-12 months of age. In conclusion, obtained troponin values in this study could be values for healthy ruminants.

Keywords:

blood serum, troponins, sheep, ruminants, lactate dehydrogenase, heart, goats, creatine kinase, cattle, blood chemistry, aspartate aminotransferase,

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