Yanakta kaşıntılı arkiform eritemli plak lezyon: Jessner-Kanof Hastalığı

Jessner'in lenfositik infiltrasyonu (JLİ) sıklıkla baş boyun bölgesinde yerleşim gösteren pembe-donuk kırmızı renkte papül, plak ya da nodüler lezyonlarla karakterize, asemptomatik, kronik seyirli lenfoproliferatif bir dermatozdur. Hastalığın farklı bir antite mi olduğu yoksa diskoid lupus eritematozus ya da polimorf ışık erüpsiyonu spektrumuna ait bir tablo mu olduğu net değildir. 34 yaşında bayan hasta yüzün sağ tarafında hafif kaşıntılı kızarıklık ve kabarıklık şikâyeti ile kliniğimize başvurdu. Klinik ve histopatolojik bulgularla hastaya Jessner'in lenfositik infiltrasyonu tanısı kondu. Bu olgu sunumunda Jessner'in lenfositik infiltrasyonunun klinik ve histopatolojik özellikleri vurgulanmakta, klinik ve histopatolojik olarak benzediği dermatozlar ile ayrıt edici özellikleri tartışılmaktadır.

Anahtar Kelimeler:

Deri ve bağ dokusu hastalıkları, ilaç döküntüleri, lupus eritematozus, diskoid

Pruritic arciform erythematous plaque on the cheek: A case of Jessner-Kanof Disease

Jessner's lymphocytic infiltration (JLI) is a skin condition of unknown aetiology characterized by the presence of red, tumid nodules, usually on the head, neck and upper back. It is not certain whether JLI is a different entity or it is a variant of discoid lupus erythematosus or polymorphous light eruption. 34 year-old female patient applied to our clinic with asymptomatic, nonscaling, erythematous plaques on her the right side of the face. The patient was diagnosed of JLI according to clinical and histopathological findings. In this case of presentation, the clinical and histopathological features of the JLI has been described and other similar dermatosis and their distinctive features have been excluded in the discussion.

Keywords:

Skin and connective tissue diseases, drug eruptions, lupus erythematosus, discoid,

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1) Shakhnes IE, Malygina LA. [Jessner-Kanof lymphocytic infiltration]. Vestn Dermatol Venerol. 1985(2):66-8. 2) Pietrzykowska A, Smigla A. [Lymphocytic infiltration Jessner-Kanof]. Przegl Dermatol. 1967;54(3):361-8. 3) Lipsker D, Mitschler A, Grosshans E, Cribier B. Could Jessner's lymphocytic infiltrate of the skin be a dermal variant of lupus erythematosus? An analysis of 210 cases. Dermatology. 2006;213(1):15-22. 4) Toonstra J, Wildschut A, Boer J, Smeenk G, Willemze R, van der Putte SC, et al. Jessner's lymphocytic infiltration of the skin. A clinical study of 100 patients. Arch Dermatol. 1989;125(11):1525-30. 5) Toonstra I, van der Putte SC, de la Faille HB, van Vloten WA. Familial Jessner's lymphocytic infiltration of the skin, occurring in a father and daughter. Clin Exp Dermatol. 1993;18(2):142-5. 6) Remy-Leroux V, Leonard F, Lambert D, Wechsler J, Cribier B, Thomas P, et al. Comparison of histopathologic-clinical characteristics of Jessner's lymphocytic infiltration of the skin and lupus erythematosus tumidus: Multicenter study of 46 cases. J Am Acad Dermatol. 2008;58(2):217-23. 7) Poenitz N, Dippel E, Klemke CD, Qadoumi M, Goerdt S. Jessner's lymphocytic infiltration of the skin: a CD8+ polyclonal reactive skin condition. Dermatology. 2003;207(3):276-84. 8) Romanenko VN, Protsenko TV. [Acase of Jessner-Kanof lymphocytic infiltration of the skin]. Vestn Dermatol Venerol. 1988(5):55-7. 9) Viljaranta S, Ranki A, Kariniemi AL, Nieminen P, Johansson L. Distribution of natural killer cells and lymphocyte subclasses in Jessner's lymphocytic infiltration of the skin and in cutaneous lesions of discoid and systemic lupus erythematosus. Br J Dermatol. 1987;116(6):831-8. 10) Tenhave-Opbroek AA. [Thoughts on the differential diagnosis of chronic discoid lupus erythematosus and "lymphocytic infiltration of the skin" (Jessner), among other things by using fluorescent microscopy]. Ned Tijdschr Geneeskd. 1965;109(36):1677. 11) Schepis C, Lentini M, Siragusa M, Batolo D. ACEinhibitor-induced drug eruption resembling lymphocytic infiltration (of Jessner-Kanof) and Lupus e r y t h e m a t o s u s t u m i d u s. D e r m a t o l o g y. 2004;208(4):354-5. 12) Abele DC, Anders KH, Chandler FW. Benign lymphocytic infiltration (Jessner-Kanof): another manifestation of borreliosis? J Am Acad Dermatol. 1989;21(4 Pt 1):795-7. 13) Caroli UM, Berner D, Schlegel C, Metzler G, Rocken M, Biedermann T. Lymphocytic infiltration of the skin Jessner-Kanof after treatment with a hydroquinone-containing bleaching cream. Arch Dermatol. 2006;142(12):1655-6. 14) Kuo TT, Lo SK, Chan HL. Immunohistochemical analysis of dermal mononuclear cell infiltrates in cutaneous lupus erythematosus, polymorphous light eruption, lymphocytic infiltration of Jessner, and cutaneous lymphoid hyperplasia: a comparative differential study. J Cutan Pathol. 1994;21(5):430-6. 15) Castri M, Silvestri T. [Clinical, histological and ultrastructural aspects of a case of Jessner-Kanof cutaneous lymphocytic infiltration]. Pathologica. 1980;72(1022):875-9. 1 6 ) Will emz e R, Ve rme e r BJ, Me ij e r CJ. Immunohistochemical studies in lymphocytic infiltration of the skin (Jessner) and discoid lupus erythematosus. A comparative study. J Am Acad Dermatol. 1984;11(5 Pt 1):832-40. 17) Borges da Costa J, Boixeda P, Moreno C. Pulsed-dye laser treatment of Jessner lymphocytic infiltration of the skin. J Eur Acad Dermatol Venereol. 2009;23(5):595-6. 18) Rai VM, Balachandran C. Multiple infiltrated nodules and plaques. Lymphocytic infiltrate of Jessner. Dermatol Online J. 2006;12(7):26.