Bahattin TUNÇ, Suna EMİR, Arzu ERDEM YAZAL, Hacı Ahmet DEMİR

Kanserli Çocuklarda İştah Uyaranı Olarak Siproheptadin Kullanımı

Giriş: Çocuk kanser hastalarında beslenme bozukluğu sıklıkla görülür. Buhastalarda beslenme durumlarının değerlendirilmesi çok önemlidir. En iyi yaklaşımbu çocuklarda iştahı arttırarak oral gıda alımını arttırmaktır. Kronik hastalığıolan çocuklarda siproheptadin ile iştah artışının uyarılmasını destekleyen bazıçalışmalar vardır. Bu çalışmada amacımız kanserli çocuklarda iştahı arttırarak oralgıda alımını arttırmak amacıyla kullandığımız siproheptadin ile ilgili deneyimimizipaylaşmaktır. Gereç ve Yöntem: İştah arttırmak için siproheptadin kullanan 14 hastanındosyaları geriye dönük olarak incelendi. Tedavi başlangıcında, 4. ve 8. hafta vücutağırlığı, boy, vücut kitle indeksi, yaşa göre ağırlık Z skorları, iştah durumu ve yanetkiler kayıt edildi. Bulgular: Siproheptadin yaşları 2,25 ile 16,5 arasında değişen (median: 4,5 yıl)14 hastada kullanıldı. On bir hastada (%78) 4. ve 8. hafta ölçümlerde kilo artışısaptandı. Hastaların ilk ay ortalama ağırlık artışı 1,44 kg olarak bulundu (p

Use of Cyproheptadine as an Appetite Stimulant in Children with Cancer

Introduction: Malnutrition is frequently seen in pediatric cancer patients. It isvery important to evaluate the nutritional status at diagnosis in these patients. Thepreferable method to treat cancer associated malnutrition in children is to increasetheir oral food intake with the help of stimulating their appetite. There are somestudies supporting the use of appetite stimulants in patients with chronic illness. Inthis report, our aim is to share our experience with cyproheptadine as an appetitestimulant in children with cancer. Materials and Methods: The medical records of 14 children who were usedcyproheptadine as an appetite stimulant were retrospectively evaluated. Theirweight, height, body mass index, weight for age Z-score, appetite status and sideeffects were recorded at baseline, 4th week and 8th week. Results: Cyproheptadine was used in fourteen patients with a median age of 4.5(range:2.25-16.5 years). Eleven of them demonstrated a response to cyproheptadine(average weight gain was 1.44 kg) Mean weight-for-age z-score was increasedfrom -2.22 to -1.56 (p

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