Probiyotikler ve Alerji

Probiyotikler, yeterli miktarlarda alındığında geleneksel beslenme etkilerinin ötesinde sağlık üzerinde olumlu etki gösteren canlı mikroorganizmalar olarak tanımlanmaktadır. Probiyotiklerin söz konusu olumlu etkilerinden biri bağırsak metabolizmasına etki ederek mukozal bağışıklığı uyarmasıdır. Son zamanlarda yapılan birçok çalışmada atopik egzema, astım ve diğer alerjileri kapsayan atopik hastalıklar ile gıda allerjilerinin belirtilerinin tedavisinde ve bunlardan korunmada bağırsaklarda kolonize olan bakterilerin rollerinden bahsedilmektedir. Probiyotiklerin mukozal bariyer fonksiyonunu geliştirerek allerjik reaksiyon üzerinde yararlı etki gösterdiği ve bunun yanında küçük çocuklar tarafından probiyotik tüketiminin bağışıklık sisteminin gelişimini olumlu yönde etkileyebildiği bildirilmektedir. Lactobacillus rhamnosus, Lactobacillus acidophilus ve Bifidobacterium bifidum gibi probiyotikler süt proteininin neden olabileceği gıda allerjilerinin tedavisinde kullanılmaktadır. Örneğin Lactobacillus rhamnosus ’un muhtemelen bu proteinleri daha küçük peptidlere ve amino asitlere parçalamak suretiyle etki ettiği belirlenmiştir. Söz konusu bakterinin diyetlerine ilave edilen çocuklarda atopik dermatit belirtilerini azalttığı da tespit edilmiştir. Yeni doğan bebeklerde probiyotik kullanımı onları çocukluk döneminde oluşabilecek alerjilerden koruyabilmektedir. Özellikle son yıllarda alerjik hastalıkların sık görülmesi sonucu konu ile ilgili çalışmalar artmakta ve Batılı toplumlarda bu hastalıkların tedavisinde toz, jel veya kapsül formunda probiyotikler kullanılmaktadır.

Anahtar Kelimeler:

Probiyotik, alerji, atopik dermatit

Probiotics and Allergy (Turkish with English Abstract)

“Probiotic” is defined as live microorganisms which promote health in addition to effects of traditional nutrition when used adequately. One of the mentioned effects of probiotics is to stimulate mucosal immunity by effecting gut metabolism. Several recent studies have suggested a role for gut-colonising bacteria in preventing and treating manifestations of food allergy and atopic disease, including atopic eczema, asthma and other allergies. It is also mentioned that probiotics have beneficial effects on allergic reactions by improving mucosal barrier function and moreover probiotic consumption by children can effect the improvement of immunity system. Probiotics such as Lactobacillus rhamnosus, Lactobacillus acidophilus and Bifidobacterium bifidum are used in treatment of food allergies associated with milk protein. For instance it is suggested that Lactobacillus rhamnosus can effect probably by breaking proteins into smaller peptides and amino acids. It is also determined that adding this bacteria to the diets of children, alleviates the symptoms of atopicdermatit. Probiotic consumption by new-born infants can also prevent them from allergies that can occur during childhood. The prevalence of allergic diseases has increased, particularly in recent years so that the number of research is increasing. In Western societies probiotics are used in powder, gel or capsule forms in the treatment of allergic diseases.

Keywords:

Probiotic, allergy, atopicdermatit ,

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