İntrakranial lipomlar: Yerleşim yerleri ile birlikte bilgisayarlı tomografi ve manyetik rezonans görüntüleme bulguları

Amaç: Bu çalışmanın amacı, nadir doğumsal malformasyonlardan olan intrakranial lipomların bilgisayarlı tomografi (BT) ve manyetik rezonans görüntüleme (MRG) bulgularını incelemek, klinik bulgularını ve birliktelik gösterdikleri malformasyonları tespit etmek ve lezyon yerleri ile hem semptomlar hem de kalfikasyon varlığı arasındaki ilişkiyi tespit etmektir. Gereç ve yöntem: Mart 2010-Mart 2015 tarihleri arasında tanı alan intrakranial lipoma sahip 57 hastanın (22 erkek ve 35 kadın, ortalama yaş 50, 2-89 arası yaş) BT ve MRG bulgularını geriye dönük değerlendirdik. 25 hastanın BT, 32 hastanın MRG incelemesi mevcuttu. Lezyonların BT dansiteleri ölçüldü, görüntüleme bulguları, lezyon hacimleri, semptomlar ve birliktelik gösterdikleri lezyonlar tespit edildi. Lezyon yerleri ile hem semptomlar hem de kalsifikasyon varlığı arasındaki ilişki kikare testi kullanılarak araştırıldı. Bulgular: Lezyonların yerleşim yerleri şu şekilde izlendi; interhemisferik fissür (n=22), sol kuadrigeminal sistern (n=10), korpus kallozum (n=10), interserebellar fissür (n=4), sağ kuadrigeminal sistern (n=3), interpedinküler sistern (n=3), silvian fissür (n=2), koroid pleksus (n=2), sol akustik kanal (n=1). Ortalama lipom hacmi 4±3,047 mm3 idi. En sık semptom 9 hastada görülen baş ağrısı idi. Lezyon yerleri, ne semptomlar (p=0,394) ile ne de kalsifikasyon varlığı (p=0,552) ile anlamlı ilişki göstermedi. Sonuç: BT ve MRG tipik özellikleriyle intrakranial lipomlara tanı koyabilmektedir ve de bu lezyonların birliktelik gösterdikleri diğer malformasyonları da ortaya koyabilmektedir. BT ve MRG özelliklerinin bilinmesi ayırıcı tanıyı kolaylaştırmaktadır.

Intracranial lipomas: Lesion localizations, computed tomography and magnetic resonance imaging findings

Objectives: The purpose of this study is to evaluate computed tomography (CT) and magnetic resonance imaging (MRI) findings of intracranial lipomas which are rare congenital malformations, to determine clinical findings and associated malformations, and to determine the relationships between lesion localization and symptoms as well as between lesion localization and presence of calcifica- tion. Material and methods: We retrospectively evaluated CT and MRI findings of 57 patients (22 male and 35 female patients) with median age of 50 who received a diagnosis of intracranial lipoma between March 2010 and March 2015. CT examina- tions of 25 patients and MRI examinations of 32 patients were available. CT densities of lesions were assessed, imaging findings, lesion volumes, symptoms, and associated lesions were determined. The relationships between lesion localization and symptoms as well as between lesion localization and presence of calcification were evaluated using using x2 test. Results: Localizations of the lesions were as follows; interhemispheric fissure (n=22), left quadrigeminal cistern (n=10), corpus callosum (n=10), intercerebellar fissure (n=4) right quadrigeminal cistern (n=3), interpeduncular cistern (n=3), sylvian fissure (n=2), choroid plexus (n=2), and left acoustic canal (n=1). Mean lipoma volume was 4±3,047 mm3. The most common symptom was headache demonstrated in 9 patients. Lesion localizations did not show any significant relationship neither with symptoms (p=0,394) nor with presence of calcification (p=0,552). Conclusion: CT and MRI can diagnose intracranial lipomas with typical findings and detect associated malformations. To know CT and MRI findings of them makes it easier to differentiate them from the other lesions.

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