Mubin HOŞNUTER, Sacide ÇOLAK, Gamze Numanoğlu YURDAKAN, Banu D. GÜN, Süheyla BOSTAN, Oğuz ÖZDAMAR

Idıopathic scrotal calcinosis with polypoid appearance

İdiopatik skrotal kalsinozis, skrotum derisinde çok sayıda sert nodüllerin varlığıyla karakterizedir. Nodüler kalsifikasyonlar tipik olarak yaşamın 2. dekatında görülür. Bu lezyonlar asemptomatik, yuvarlak sert papüller durumundadır. Olgu 53 yaşında skrotumda ağrısız, sert nodüller ile başvurdu. Lezyonların 23 yaşında iken görülmeye başladığı ve bazılarının zamanla ilerleyerek polipoid forma dönüştüğü öğrenildi. Hastanın öyküsünde travma veya cerrahi tedavi yoktu. Serum kalsiyum, fosfor, kalsitonin ve paratiroid hormon seviyeleri normal sınırlardaydı. Kistlerin histopatolojik incelemesinde epitelle döşeli olmayan keratin içeriklerinin distrofik kalsifikasyonu görüldü. Bilgilerimize göre bu olgu literatürde bildirilen polipoid görünümlü ikinci skrotal kalsinozis olgusudur.

Polipoid görünümlü idiopatik skrotal kalsinozis

Idiopathic scrotal calcinosis is characterized by the presence of multiple firm nodules of scrotal skin. The nodular calcifications are typically found in the second decade of life. The lesions are seen as asymptomatic, round, firm papules. A 53-year-old man was admitted with painless, firm nodules within the scrotum. The lesions had begun to appear at the age of 23 years and some of them had become polypoid progressively over time. There was no trauma or previous surgical treatment. The serum levels of calcium, phosphorus, calcitonin, and parathyroid hormone were within normal limits. The polypoid masses were surgically excised. Histological examination of the cysts revealed dystrophic calcification of their keratin contents but no epithelial lining. To the best of our knowledge, this is the second case of scrotal calcinosis with polypoid appearance in the literature.

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1. Saad AG, Zaatari GS, Scrotal calcinosis: is it idiopathic? Urology. 2001; 57: 365.
2. Rosai J Male Reproductive System, In: Rosai and Ackerman’s Surgical Pathology, Ninth Ed, Vol: 1, Philadelphia, Mosby 2004; p: 1313
3. Mills SE, Nonneoplastic Diseases of the Skin In: Sternberg’s Diagnostic Surgical Pathology, Fourth Ed, Vol: 1, Philadelphia, by Lippincott Williams & Wilkins 2004; pp: 39- 40
4. http://www.bweems.com/idioscrcal.html Scrotal calcinosis 5. http://www.archderm.ama-assn.org/cgi/content/abstract/118/12/985 Swinehart JM, Golitz LE. Scrotal calcinosis. Dystrophic calcification of epidermoid cysts
6. Moskovitz B, Bolkier M, Ginesin Y, Levin DR, Bassan L. Idiopathic calcinosis of scrotum. Eur Urol 1987; 13: 130-131.
7. Soldre CT, Azulay DR, Carneiro S, Azulay DR. [Calcinosis of the scrotum] Med Cutan Ibero Lat Am 1986; 14: 275-280.
8. Kumagai K, Amemiya H, Muramatsu H, Kariba T, Matsuse K, Toyoshima A, Yazaki T, Waku M, Okada N. Idiopathic calcinosis of the scrotum: a case report Hinyokika Kiyo 1987; 33:1289-1291.
9. Fetsch JF, Montogomery EA, Meis JM. Calcifying fibrous pseudotumor Am J Surg Pathol 1993; 17(5): 502-508.
10. Moshin SK, Lee MW, Amin MB, Stoler MH, Eyzaguirre E, Ma CK, Zarbo RJ. Cutaneous verruciform xanthoma: a report of five cases investigating the etiology and nature of xanthomatous cells. Am J Surg Pathol 1998; 22(4): 479-487.
11. Polk P, McCutchen WT, Phillips JG, Biggs PJ. Polypoid scrotal calcinosis: an uncommon variant of scrotal calcinosis. South Med J 1996; 89(9): 896-897.