Mustafa Kemal SARIBAY, Gökhan DOĞRUER, Fikret KARACA

Repeat breeder sorunlu düvelerde fluniksin meglumin uygulamalarının gebelik oranı üzerine etkisi

Bu çalışma repeat breeder sorunlu düvelerde tohumlama sonrası 15-16. günlerde iki kez fluniksin meglumin (FM) enjeksiyonunun, gebelik oranı üzerine etkisinin incelenmesi amacıyla yapıldı. Araştırma, klinik olarak herhangi bir sorunu bulunmayan, düzenli siklus gösteren, en az üç kez tohumlandığı halde gebe kalmayan, yaşları 19-31 ay arasında değişen 20 baş holstein ırkı düve üzerinde gerçekleştirildi. Tüm hayvanlara 14 gün arayla çift doz 150 mcg PGF2α (D- Cloprostenol, Dalmazin, Vetaş) ve ikinci PGF2α enjeksiyonundan 48 saat sonra 10 mcg GnRH (Buserelin acetate, Receptal, Intervet) kas içi enjekte edildi. Düveler GnRH enjeksiyonundan 12-14 saat sonra tohumlandı. Tohumlama sonrası 15. günde düveler tesadüfi örnekleme yolu ile iki gruba ayrıldı. Deneme grubunda (n=10) bulunan düvelere tohumlamalardan sonraki 15. günün akşamı ve 16. günün sabahında 12 saat arayla iki kez 1.1 mg/kg dozunda FM (Fulimed, Alke) kas içi enjekte edildi. Kontrol grubu (n=10) düvelere herhangi bir uygulama yapılmadı. Tohumlamalardan 29 gün sonra ultrasonografi ile yapılan gebelik muayenelerinde, deneme grubunda 5 ( % 50), kontrol grubunda 2 (% 20) düvenin gebe olduğu tespit edildi. Deneme ve kontrol grubu düvelerde gebelik oranları arasında istatistiki farklılık bulunmamakla birlikte deneme grubunda gebeliklerin daha yüksek olduğu gözlendi. Sonuç olarak repeat breeder sorunlu düvelerde tohumlama sonrası 15-16. günlerde FM uygulamalarının gebelik oranı üzerine olumlu katkı sağlayabileceği kanısına varıldı.

The effects of flunixin meglumine administrations on the pregnancy rate at repeat breeding

This study was carried out to determine the effect of double flunixin meglumine (FM) injection per day at 15-16 days post insemination, on the pregnancy rates of repeat breeding heifers. Twenty Holstein heifers; ages ranging between 19-31 months were used as the research materials. The heifers were clinically healthy, having regular estrus cycles but returned after having been at least three times inseminated. PGF2α (D-cloprostenol, Dalmazin, Vetaş) at a dose of 150 mcg was injected twice intramuscularly at 14 days intervals, 48 hours after the last PGF2α injection 10 mcg GnRH (Buserelin acetate, Receptal, İntervet) was injected intramuscularly and a timed artificial insemination was performed between 12-14 hours after buserelin injection. Heifers were randomly assigned to two groups at the 15th day post insemination. Flunixine meglumine (Fulimed, Alke) at a dose of 1.1 mg/kg was injected to the treatment group in the evening of the 15th and in the morning of the 16th days (12 h intervals) post insemination. No application was performed to control group.The ultrasonographic examination performed at the 29th day post insemination indicated that 5 heifers (%50) were pregnant in the treatment group, while only 2 heifers (%20) were pregnant in the non-treated control group. The differences between two groups were not found to be statistically significant but the pregnancy rate was found to be higher treatment group than the control group.It was concluded that flunixine meglumine applications to repeat breeding heifers at the15-16th days post insemination, may be useful for increasing the pregnancy rates

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