Bir Meta-analizi Nasıl Okunur? Klinisyenler için Bir Kılavuz

Meta-analizi aynı amaçla gerçekleştirilen ilgili çalışmaların sonuçlarını birleştiren ve kanıta dayalı tıpta karar vermeyi desteklemek için kullanılan bir araçtır. Meta-analizleri ileri istatistiksel analizler içerdiğinden, sonuçlar klinisyenler için kolayca anlaşılabilir değildir. Bu çalışmada, klinisyenlerin bir meta-analizin istatistiksel analiz bölümünü anlamalarına, sonuçlarını ve grafiklerini yorumlamalarına yardımcı yardımcı olmak bir kılavuz yazmayı amaçladık.

How to Read a Meta-Analysis? A Guideline for Clinicians

Meta-analysis is a statistical analysis that combines the results of relevant studies performed for same purpose and is used as a toolfor evidence-based medicine to support clinical decision making. Because a meta-analysis includes advanced statistical analysis,the report is not easily understandable to clinicians. In this study, we aimed to write a guideline for clinicians to help them understand the statistical analysis part of a meta-analysis and interpret graphs and results of a meta-analysis.

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Leandro G. Meta-analysis in Medical Research: The handbook for the understanding and practice of meta-analysis. 2th ed. John Wiley & Sons; 2008, p. 57-61.
Haidich AB. Meta-analysis in medical research. Hippokratia. 2010; 14: 29.
DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986; 7: 177-8. [CrossRef]
Egger M, Schneider M, Smith GD. Spurious precision? Meta-analysis of observational studies. BMJ 1998; 316:140-4. [CrossRef]
Van Tulder M, Furlan A, Bombardier C, Bouter L, Editorial Board of the Cochrane Collaboration Back Review Group. Updated method guidelines for systematic reviews in the cochrane collaboration back review group. Spine (Phila Pa 1976) 2003; 28: 1290-9. [CrossRef]
Higgins JPT, Green S. Cochrane handbook for systematic reviews of interventions version 5.1.0. (Updated March 2011) The Cochrane collaboration. http://www.cochrane-handbook.org. Accessed February 2, 2018.
Moher D, Liberati A, Tetzlaff J, Altman DG, Group P. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med 2009; 6: e1000097. [CrossRef]
Russo MW. How to review a meta-analysis. Gastroenterol Hepatol 2007; 3: 637-42.
Ried K. Interpreting and understanding meta-analysis graphs: a practical guide. Aust Fam Physician 2006; 35: 635-8.
Kul S, Barbieri A, Milan E, Montag I, Vanhaecht K, Panella M. Effects of care pathways on the in-hospital treatment of heart failure: a systematic review. BMC Cardiovasc Disord 2012; 12: 81. [CrossRef]
Zhang J, Yu KF. What’s the relative risk? A method of correcting the odds ratio in cohort studies of common outcomes. JAMA 1998; 280: 1690-1. [CrossRef]