Hüban GÖÇMEN, Halit ŞÜKÜR, Hazel TAMAKAN, Ömer Memduh ESENDAL

Kuzey Kıbrıs Türk Cumhuriyeti’nde Hayvanlardan İzole Edilen Stafilokok Türlerinin Metisilin Dirençliliği Üzerine Retrospektif Bir Çalışma

İnsanlarda ve hayvanlarda normal floranın bir parçası olarak kabul edilen stafilokokların bazı türleri, hayvanların ve insanların vücut bölgelerinde (örneğin; deri, kulak, eklem) çok çeşitli piyojenik infeksiyonlara neden olabilmektedir. Özellikle metisilin dirençliliği ile halk sağlığı açısından tehdit oluşturan stafilokok türlerinin başında Staphylococcus aureus gelmektedir. Bunu takiben S. pseudintermedius ve son zamanlarda da koagülaz negatif stafilokoklar sayılabilmektedir.

Anahtar Kelimeler:

Evcil hayvanlar, Metisilin dirençliliği, Stafilokok türleri

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1. Beck KM, Waisglass SE, Dick H LN, Weese JS, (2012). Prevalence of meticillin-resistant Staphylococcus pseudintermedius (MRSP) from skin and carriage sites of dogs after treatment of their meticillin-resistant or meticillin-sensitive staphylococcal pyoderma. Vet Dermatol. 23, 369–375.
2. Bochev I, Russenova N, (2005). Resistance of Staphylococcus spp. strains isolated from goats with subclinical mastitis. Bulg J Vet Med. 8, 2, 109-118.
3. Chiers K, Decostere A, Devriese LA, Haesebrouck F, (2003). Bacteriological and mycological findings, and in vitro antibiotic sensitivity of pathogenic staphylococci in equine skin infections. Vet Rec. 138–40.
4. Davis JA, Jackson CR, Fedorka-Cray PJ, Barrett JB, Brousse JH, Gustafson J, Kucher M, (2014). Carriage of methicillin- resistant staphylococci by healthy companion animals in the US. Letters in Applied Microbiology. 59, 1-8.
5. Devriese LA, Hommez J, (1975). Epidemiology of methicillin- resistant Staphylococcus aureus in dairy herds. Res Vet Sci. 1, 23–7.
6. Devriese LA, Vancanneyt M, Baele M. et al, (2005). Staphylococcus pseudintermedius sp. nov., a coagulase-positive species from animals. Int J Syst Evol Microbiol. 55, 1569– 73.
7. Duijkeren VE, Box A T A, Heck M E O C, Wannet W J B, Fluit A C, (2004). Methicillin-resistant staphylococci isolated from animals. Vet Microbiol. 103, 91-97.
8. El-Deeb W, Fayez M, Elmoslemany A, Kandeel M, Zidan K, (2018). Methicillin resistant Staphylococcus aureus among goat farms in Eastern province, Saudi Arabia: Prevalence and risk factors. Prev Med Vet. 156, 84-90.
9. Fazakerley J, Nuttall T, Sales D et al, (2009). Staphylococcal colonization of mucosal and lesional skin sites in atopic and healthy dogs. Vet Dermatol. 20, 179–184.
10. Feng Y, Tıan W, Lın D, Luo Q, Zhou Y, Yang T, Deng Y, Lıu Y H, Lıu J H, (2012). Prevalence and characterization of methicillin-resistant Staphylococcus pseudintermedius in pets from South China. Vet Microbiol. 160, 517-24.
11. Gentilini E, Denamiel G, Betancor A, Rebuelto M, Rodriguez M, De Torrest RA, (2002). Antimicrobial susceptibility of coagulase negative staphylococci isolated from bovine mastitis in Argentina. J Dairy Sci. 85, 1913-1917.
12. Guardabassi L, Loeber M, Jacobson A, (2004). Transmission of multiple antimicrobial-resistant Staphylococcus intermedius between dogs affected by deep pyoderma and their owners. Vet Microbiol. 98, 23–27.
13. Hanselman B A, Kruth S A, Rousseau J et al., (2009). Coagulase positive staphylococcal colonization of humans and their household pets. Can Vet J. 50, 954–958.
14. Hartmann FA, Trostle SS, Klohnen AA, (1997). Isolation of methicillin resistant Staphylococcus aureus from a postoperative wound infection in a horse. J Am Vet Med Assoc. 211, 1558–61.
15. Hosseinzadeh S, Saei HD, (2014). Staphylococcal species associated with bovine mastitis in the north west of Iran: Emerging of coagulase-negative staphylococci. Int J Vet Sci Med. 2, 27-34
16. Kadlec K, Schwarz S, Perreten V et al., (2010). Molecular analysis of methicillin-resistant Staphylococcus pseudintermedius of feline origin from different European countries and North America. J Antimicrob Chemother. 65, 1826–8.
17. Kawakami T, Shibata S, Murayama N, Nagata M, Nishifuji K, Iwasaki T, Fukata T, (2010). Antimicrobial susceptibility and methicillin resistance in Staphylococcus pseudintermedius and Staphylococcus schleiferi subsp. coagulans isolated from dogs with pyoderma in Japan. Journal of Veterinary Medical Science. 72, 1615–1619.
18. Lina G, Etienne J, Vandenesch F, (2000). Biology and pathogenicity of staphylococci other than Staphylococcus aureus and Staphylococcus epidermidis. pp: 450-462. In Fischetti VA, Novick RP, Ferretti JJ, Portnoy DA, Rood JI (EDS), Gram Positive Pathogens. ASM Press, Washington DC.
19. Moeller RW, Smith IM, Shemaker AC, Tjalma RA, (1963). Transfer of hospital staphylococci from man to farm animals. J Am Vet Med Assoc. 142, 613–7.
20. Morris DO, Rook KA, Shofer FS et al., (2006). Screening of Staphylococcus aureus, Staphylococcus intermedius, and Staphylococcus schleiferi isolates obtained from small companion animals for antimicrobial resistance: a retrospective review of 749 isolates (2003–04). Vet Dermatol. 17, 332–7.
21. Obaidat M, Bani Salman Alaa E, Roess Amira A, (2017). High prevalence and antimicrobial resistance of mecA Staphylococcus aureus in dairy cattle, sheep, and goat bulk tank milk in Jordan. Trop Anim Health Prod. 50, 2, 405- 412.
22. Pantosti A, (2012). Methicillin- resistant Staphylococcus aureus associated with animals and its relevance to human health. Frontiers in Microbiology. 3, 127.
23. Pitkälä A, Haveri M, Pyörälä S, Myllys V, Honkanen-Buzalski T, (2004). Bovine mastitis in Finland 2001-prevalence, distrubition of bacteria, and antimicrobial resistance. J Dairy Sci. 87, 2433- 2441.
24. Quinn PJ, Carter ME, Markey B, Carter GR, (1994). Staphylococcus species. In Clinical Veterinary Microbiology. Wolfe Publishing. 118-126.
25. Rich M, (2005). Staphylococci in animals: prevalence, identification and antimicrobial susceptibility, with an emphasis on methicillin-resistant Staphylococcus aureus. British Journal of Biomedical Science. 62,2, 98-105.
26. Sareyyüpoğlu B, Müştak HK, Cantekin Z, Diker KS, (2014). Methicillin Resistance in Staphylococcus pseudintermedius Isolated from Shelter Dogs in Turkey. Kafkas Universitesi Veteriner Fakültesi Dergisi. 20, 3, 435-438.
27. Sasaki T, Kikuchi K, Tanaka Y et al., (2007). Reclassification of phenotypically identified Staphylococcus intermedius strains. J Clin Microbiol. 45, 2770–8.
28. Seguin JC, Walker RD, Caron JP, Kloos WE, George CG, Hollis RJ, Jones RN, Pfaller MA, (1999). Methicillinresistant Staphylococcus aureus outbreak in a veterinary teaching hospital: potential humanto-animal transmission. J Clin Microbiol. 37, 1459–1463.
29. Shimizu A, Kawano J, Yamamoto C, Kakutani O, Anzai T, Kamada M, (1997). Genetic analysis of equine methicillinresistant Staphylococcus aureus by pulsed-field gel electrophoresis. J Vet Med Sci. 59, 935–937.
30. Shuttleworth RR, Behme RJ, McNabb A, Colby WD, (1997). Human isolates of Staphylococcus caprae: Association with bone and joint infections. J Clin Microbiol. 35, 2537-2541.
31. Spohr M, Rau J, Friedrich A, Klittich G, Fetsch A, Guerra B, Hammerl JA, Tenhagen BA (2011). Methicillin-resistant Staphylococcus aureus (MRSA) in three dairy herds in southwest Germany. Zoonoses Public Health. 58, 4, 252- 61.
32. Tenhagen BA, Koster G, Wallmann J, Heuwieser W, (2006). Prevalence of mastitis pathogens and their resistance against antimicrobial agents in dairy cows in Brandenburg, Germany. J Dairy Sc. 89, 2542-2551.
33. Virdis S, Scarano C, Cossu F, Spanu V, Spanu C, De Santis E P L, (2010). Antibiotic resistance in Staphylococcus aureus and coagulase negative staphylococci isolated from goats with subclinical mastitis. SAGE-Hindawi Accessto Research, Veterinary Medicine International.
34. Weese JS, Duijkeren E, (2010). Methicillin resistant Staphylococcus aureus and Staphylococcus pseudintermedius in veterinary medicine. Vet Microbiol. 140, 3-4, 418–429.
35. Yasuda R, Kawano J, Onda H, Takagi M, Shimizu A, Anzai T, (2000). Methicillin resistant coagulase negative staphylococci isolated from healthy horses in Japan. Am J Vet Res. 61, 1451–1455.