1915

Ortak Ataları Olan İki Alman Holştayn Buzağıda Konjenital Damak-Dudak-Çene Yarığı ve Damak Yarığı Olgusu

Ataları ortak olan iki buzağıda yapılan bu çalışma da sert damak kemiğine kadar uzanan bir damak yarığı olgusu sunulmaktadır. Birinci olgu, dişi bir aylık Alman Holştayn buzağı olup; dudak-damak ve çene yarığı ile beraber sağ rostral beyin hemisferi, bulbi olfactorii ve chiasma opticum’u ayrılmış olarak görüldü. Buna ek olarak, yüzünün sol tarafında bir meningosel mevcuttu. Buzağının dili sol tarafa aşağıya doğru asılı olarak duruyordu. İkinci olgu ise erkek Alman Holştayn buzağı olup iki aylık iken incelemesi yapıldı. Bu buzağı da ise tüm damak kemiği uzunluğu boyunca uzanan bir yarık damak (CP) olgusu gözlemlendi. Buzağılarda başka organ anomalileri görülmedi. Buzağılar farklı çiftliklerden gelmiştir. Her iki buzağıda da ağır seyreden bir bronkopnömoni tablosu bulunmaktadır. Buna ek olarak ikinci erkek buzağıda şiddetli bir ishal vardı. Her iki buzağınında bovine viral diare (BVD) virüs antikoru ve antijeni yönünden negatif olduğu belirlendi. Buzağıların ikisinde hem anne hem baba tarafından dört ortak atasının olduğu belirlendi. Ortak soydan gelen genetik faktörlerin her iki buzağıda gözlenen malformasyonların sebebi olabileceği düşünüldü.

Anahtar Kelimeler:

anomali, dudak-damak-çene yarığı, Holştayn, konjenital, sığır

Congenital cleft lip-jaw-palate and cleft palate in German Holstein Calves with Common Ancestry

In this study two calves with cleft palate extending over the full length of the osseous palate and common ancestors are presented. The first case, a female German Holstein calf was one month old at examination and showed a cleft palate, a right sided cleft lip and jaw, diverging rostral cerebral hemispheres, bulbi olfactorii and chiasma opticum and in addition, a meningocele on the left side of the face. The tongue of the calf hung down on left side. The second case was a male German Holstein, calf examined with an age of two months. This calf had a cleft palate (CP) extending over the entire length of the osseous palate. Other inborn organ defects could not be found in both calves. The calves originated from different dairy farms. Both calves suffered from a bronchopneumonia and in addition, the second case had a severe diarrhea. Both calves were negative for bovine viral diarrhea (BVD) virus antibody and antigen. Both calves had four common ancestors from either parent. The common ancestry may be indicative for genetic factors involved in the malformation observed in both cases.

Keywords:

anomaly, cattle, cleft lip-palate, congenital, Holstein,

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