Bu çalışmada asit-peptik hastalıklara bağlı üst G/S kanamalanndan sonra omeprazol ve ranitidin tedavisinin etkinliğinin değerlendirilmesi amaçlandı. Endoskopik kontroller 4. hafta yapıldı ve iyileşmemiş hastalarda tedaviye 8. haftaya kadar devam edildi. Duodenal ülserli hastalarda iyileşme oranları 4. haftada omeprazol için % 85.7 ve ranitidin için % 66.6 idi (p0.05). Eroziv gastritti hastalardaki iyileşme oranları 4. hafta ve 8. haftada omeprazol için % 50 ve % 100 iken ranitidin için % 42.8 ve % 85.7 idi (p

The aims of the present study were to evaluate the effectiveness of omeprazole and ranitidine after upper gastrointestinal bleedings due to acid-peptic diseases. Endoscopie controls were performed at 4tn wk and if there was unhealed patient in the endoscopy, treatment was continued until 8th wk. For duodenal ulcer healing rates were 85.7 % for omeprazole and 66.6 % for ranitidine after 4 weeks (p<0.05) and for 100 % both omeprazole and ranitidine after 8 weeks (p>0.05). For erosive gastritis healing rates were 50 % for omeprazole and 42.8 % for ranitidine after 4 weeks (p<0.05) and 100% for omeprazole and 85.7 % for ranitidine (p<0.05). For gastric ulcer healing rates were 66.6 % for omeprazole and 50 %for ranitidine after 4 weeks (p<0.05) and 100% for omeprazol and 75% for ranitidine (p<0.05). Furthermore, omeprazole group was associated with a lower average daily consumption of antacid than ranitidine group (p<0.05). Omeprazole heals acid-peptic diseases greater and faster than ranitidine.