Akciğer rezeksiyonu öncesi preoperatif değerlendirme

Giriş: Akciğer rezeksiyonu yapılan olgular ameliyat sonrası gelişen komplikasyonlar açısından risk altındadır. Bu nedenle akciğer rezeksiyonu olacak hastalarda preoperatif dönemde kardiyopulmoner ve fonksiyonel kapasite değerlendirimi önemlidir. Bu çalışmada, akciğer rezeksiyonu yapılacak olan hastaların preoperatif kardiyopulmoner fonksiyonlarını, fonksiyonel kapasitelerini değerlendirmek ve bu bulguların postoperatif dönemde oluşan komplikasyonlarla ilişkisini ortaya koymayı amaçladık. Gereç ve Yöntem: Çalışmamıza rezektabl bir akciğer hastalığı olduğu düşünülen 21 hasta alındı. Hastalar preoperatif dönemdeki kardiyopulmoner fonksiyonları; solunum fonksiyon testi, kan gazı, oksijen satürasyonu, akciğer grafisi, elektrokardiyografi, ekokardiyografi ile, fonksiyonel kapasiteleri kardiyopulmoner egzersiz testi (pVO2), 6 dakika yürüme testi ve yaşam kalitesi (KF 36) ile değerlendirildi. Hastaların yoğun bakımda kalış süreleri, postoperatif komplikasyonları ve hastanede kalış süreleri kaydedildi. Bulgular: Hastaların %85.7 (n: 18 hasta) rezektabl bir akciğer malignitesi saptandı. Preoperatif klinik değerlendirme sonrası akciğer rezeksiyonunu takiben % 38.1 (n: 8) hastada komplikasyon görüldü. Komplikasyon gelişen ve komplikasyon gelişmeyen grup arasında hastanede kalış süresi dışında, diğer tüm kardiyopulmoner, fonksiyonel kapasite parametreleri açısından ilişki saptanmadı (p>0.05). Sonuç: Çalışmamızda, komplikasyonların kardiyopulmoner fonksiyonlar ve fonksiyonel kapasite parametreleri ile ilişkisi gösterilememiştir. Komplikasyonlarla kardiyopulmoner fonksiyonların ve fonksiyonel kapasitenin ilişkisini değerlendiren ve daha fazla sayıda hasta içeren çalışmalara ihtiyaç duyulmaktadır.

Preoperative evaluation of lung resection candidate

Introduction: Patients who undergo evaluation for lung resection have increased risk for the development of postoperative complications. Therefore, preoperative cardiopulmonary and functional evaluation are very important in the evaluation of lung resection candidates. We evaluated preoperative cardiopulmonary function and functional capacity of these patients and correlate them with postoperative complications. Material and Methods: 21 resectable lung cancer patients were included into the study. Patients were evaluated for cardiopulmonary functions (spirometry, blood gases, oxygen saturation, lung radiology, electrokardiography, echocardiogarphy) and functional capacity (maximal cardiopulmonary exercise test, siz minute walk test, quality of life questionnaire (SF 36). Postoperative complications, duration of hospital stay and duration of ICU (intensive care unit stay) were recorded. Results: % 85.7 patients had lung cancer. %31.8 (n:8) patients show complications after lung resection. There was no correlation between complications and cardiopulmonary functions, functional capacity (p>0.05). Duration of hospital stay found only significant who had complications (p= 0.008). Conclusion: Postoperative complications show no correlation with cardiopulmonary functions and functional capacity. Studies with more patients are needed to evaluate the relationship among complications and cardiopulmonary functions and functional capacity.

___

  • 1) López-Encuentra A, Pozo-Rodríguez F, Martín-Escribano P, et al. Surgical lung cancer. Risk operative analysis. Lung Cancer 2004 ;44 :327-37.
  • 2) İnci İ, Pabuşcu E. Preoperative evaluation in surgical treatment of lung cancer. Tuberk Toraks 2005;53 :210-20
  • 3) Cicero LJ, Ponn RB, Daly BDT. Surgical treatment of non small cell lung cancer. In: Shields TW, Lo Cicero III J, Ponn RB; eds. General Thoracic Surgery. 5th ed. Philadelphia: Lippincott Williams &Wilkins; 2000:1311-41
  • 4) Steinbaum SS, Uretzky ID, McAdams HP, et al. Exploratory thoracotomy for nonresectable lung cancer. Chest 1995 ;107 :1058-61.
  • 5) Bolliger CT. Evaluation of operability before lung resection. Curr Opin Pulm Med 2003;9 :321-6
  • 6) Akkoca Ö, Gülbay B, Altinkaya C, et al. The importance of exercise testing for the functional assessment of lung resectional candidates. Tuberk Toraks 2004;52 :307-14.
  • 7) Brunelli A, Monteverde M, Borri A, et al. Predicted versus observed maximum oxygen consumption early after lung resection.. Ann Thorac Surg 2003 ;76 :376-80.
  • 8) Cooke GA, Marshall P, Al-Timman JK, et al. Physiological cardiac reserve: development of a non-invasive method and first estimates in man. Heart. 1998;79 :289-94
  • 9) Borg GA. Psychophysical bases of perceived exertion. Med Sci Sport Exerc 1982;14:377-81
  • 10) Weisman IM, Zeballos RJ. Clinical exercise testing. Clin Chest Med 2001;22:679-701.
  • 11) Ware JE, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care 1992 ;30 :473-83
  • 12) Koçyiğit H, Aydemir Ö, Ölmez N, ve ark. SF 36'nın Türkçe geçerliliği ve güvenirliği. Ege Fizik Tedavi ve Rehabilitasyon Dergisi 1999
  • 13) Pierce RJ, Copland JM, Sharpe K, et al. Preoperative risk evaluation for lung cancer resection: predicted postoperative product as a predictor of surgical mortality. Am J Respir Crit Care Med 1994 ;150 :947-55.
  • 14) Wyser C, Stulz P, Solèr M, et al. Prospective evaluation of an algorithm for the functional assessment of lung resection candidates. Am J Respir Crit Care Med 1999 ;159:1450-6.
  • 15) Bolliger CT, Jordan P, Solèr M, et al. Exercise capacity as a predictor of postoperative complications in lung resection candidates. Am J Respir Crit Care Med 1995 ;151:1472-80.
  • 16) Melendez JA, Carlon VA. Cardiopulmonary risk index does not predict complications after thoracic surgery. Chest 1998 ;114 :69-75.
  • 17) Bolliger CT, Perruchoud AP. Functional evaluation of the lung resection candidate. Eur Respir J 1998 ;11 :198-212.
  • 18) Olsen G.N. Pulmonary physiologic assessment of operative risk. Eds.: Shields. T. W., Lo icero, J., Pon, R. B.: General Thoracic Surgery. 4 th edition, Philadelphia, PA: lippincot Williams and Wilkins, 2000, p297-304
  • 19) Akkoca Ö. Göğüs Cerrahisinde Preoperatif Değerlendirme, Eds.: Ökten İ, Güngör A. Göğüs Cerrahisi 1. baskı, Ankara, Sim Matbaacılık, 2003, s95-200
  • 20) Smetana GW. Preoperative pulmonary evaluation. N Engl J Med 1999;340 :937-44.
  • 21) Ferguson MK. Preoperative assessment of pulmonary risk. Chest. 1999 ;115 :58S-63S.
  • 22) BTS-guidelines: guidelines on the selection of patients with lung cancer surgery. Thorax 2001; 56: 89-108
  • 23) Bolliger CT, Wyser C, Roser H, et al. Lung scanning and exercise testing for the prediction of postoperative performance in lung resection candidates at increased risk for complications. Chest. 1995 ;108 :341-8.
  • 24) Brunelli A, Al Refai M, Monteverde M, et al. Stair climbing test predicts cardiopulmonary complications after lung resection. Chest. 2002 ;121 :1106-10.
  • 25) Wang JS, Abboud RT, Evans KG, et al. Role of CO diffusing capacity during exercise in the preoperative evaluation for lung resection. Am J Respir Crit Care Med 2000 ;162 :1435-44.
  • 26) Morice RC, Peters EJ, Ryan MB, et al. Exercise testing in the evaluation of patients at high risk for complications from lung resection. Chest 1992 ;101 :356-61.
  • 27) Smith TP, Kinasewitz GT, Tucker WY, et al. Exercise capacity as a predictor of post-thoracotomy morbidity. Am Rev Respir Dis 1984 ;129 :730-4
  • 28) Wang J, Olak J, Ultmann RE, et al. Assessment of pulmonary complications after lung resection. Ann Thorac Surg. 1999 ;67 :1444-7.
  • 29) Starobin D, Kramer MR, Yarmolovsky A, et al. Assessment of functional capacity in patients with chronic obstructive pulmonary disease: correlation between cardiopulmonary exercise, 6 minute walk and 15 step exercise oximetry test. Isr Med Assoc J 2006 ;8 :460-3.
  • 30) Leyenson V, Furukawa S, Kuzma AM, et al. Correlation of changes in quality of life after lung volume reduction surgery with changes in lung function, exercise, and gas exchange. Chest 2000 ;118 :728-35
  • 31) Sørensen JB, Kragstrup J, Kjaer K, et al. Exercise on prescription: trial protocol and evaluation of outcomes. BMC Health Serv Res. 2007 ;7:36.