Uğur GÜLŞEN, Hüseyin GÜLCAN, Elif Aslı GÜLŞEN

Santral Dev Hücreli Granülom Tedavisinde Kortikosteroid Kullanımı

Sık görülmeyen bir hastalık olan santral dev hücreli granülom (SDHG), neoplazik olmayan bir kemik lezyonudur. Klinik olarak asemptomatik olabilir ya da kök rezorpsiyonu, kortikal kemik yıkımı gibi agresif ve ağrılı bir durum gösterebilir. Bu olgu sunumunun amacı santral dev hücreli granülom tedavisinde daha az invaziv bir yöntem olan lezyon içi kortikosteroid enjeksiyonunun önemini vurgulamaktır. 24 yaşında kadın hasta mandibula sol bölgede ağrı ve şişlikle kliniğe başvurdu. Ağız içi muayenede, bu bölgede 6 aydır bulunduğu öğrenilen kırmızı-mor renkli şişlik tespit edildi. Radyografik muayenede multiloküler radyolüsent lezyon ve diş köklerinde rezorpsiyon tespit edildi. Lokal anestezi altında biyopsi yapıldı. Yapılan histopatolojik incelemenin ardından SDHG tanısı kondu. Hastaya lezyon içi kortikosteroid enjeksiyonu uygulandı. Rutin takiplerde lezyonun küçülüp kaybolduğu görüldü.

The Use of Corticosteroid in the Treatment of Central Giant Cell Granuloma

Central giant cell granuloma (CGCG), an infrequent disease, is a non-neoplastic bone lesion. Clinically, it may be asymptomatic or it may show an aggressive and painful condition that can cause root resorption, cortical bone destruction. The aim of this report is to emphasize the importance of intralesional corticosteroid injection, which is a less invasive technique in the treatment of CGCG. 24 years old female patient came to our clinic with pain and swelling in the left side of the mandible. In intraoral examination, a red-purple swelling, which was found to have been present for 6 months, was detected in this region. Radiographic examination showed a multilocular radiolucent lesion and root resorption. Biopsy was done under local anesthesia. After the histopathological examination, the diagnosis of CGCG was done. Intralesional corticosteroid injection was applied. During routine follow-up, the lesion was observed to decrease and disappear.

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