Özcan UZU, Caner ÇAVDAR

COVID-19 ve akut böbrek hasarı

COVID 19 başlıca solunum sistemini etkiler ancak virüs hücrelere böbrekte bol miktarda bulunan anjiyotensin dönüştürücü enzim 2 reseptörü aracılığıyla girdiğinden böbrek SARS CoV 2 enfeksiyonunun hedeflerinden biri olabilir. COVID 19 ve böbrek hakkındaki bilgiler sınırlı olmasına rağmen hızla gelişmektedir. COVID 19 hastalarında akut böbrek hasarının (ABH) patofizyolojisi ve mekanizmaları tam olarak aydınlatılmamış olup; COVID 19 ABHʹnin önlenmesi ve yönetimi hakkında çok az şey bilinmektedir. Bu derleme, COVID 19ʹda ABH patofizyolosini, klinik özelliklerini ve akut böbrek hastalığının önlenmesi ve yönetimi hakkında detaylı bilgiler sunmaktadır.

COVID-19 AND ACUTE KIDNEY INJURY

COVID 19 mainly affects the respiratory system, but as the virus enters the cells via the angiotensin converting enzyme 2 receptor, which is abundant in the kidney, the kidney may be one of the targets of SARS CoV 2 infection. Information on COVID 19 and the kidney is rapidly evolving, although yet limited. The pathophysiology and mechanisms of acute kidney injury (AKI) in COVID 19 patients have not been fully elucidated; little is known about the prevention and management of COVID 19 AKI. This review provides detailed information on the pathophysiology of AKI, clinical features, and prevention and management of acute kidney disease in COVID 19.

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