Bülent GÜVENDİ, FATİH KARA, GÜLNAME FINDIK GÜVENDİ, YASEMEN ADALI, Tugba TOYRAN, Kenan BİNNETOĞLU, Mahmut Can YAĞMURDUR

The effect of Hashimoto's thyroiditis on platelets in terms of the their number, size, and distribution

Objective: The aim of our study was to investigate whether platelet indices were affected in patients with Hashimoto’sthyroiditis (HT).Method: 11 patients (10 female, 1 male) with HT and 26 subjects with nodular goiters (19 female, 7 male) selected ascontrol group were included in the study. All cases were examined for complete blood count parameters (leukocytecount, neutrophil count and percentage, lymphocyte count and percentage, platelet count, plateletcrit, plateletdistribution width (PDW), and mean platelet volume (MPV)).Results: Leukocyte count, neutrophil count and percentage, lymphocyte percentage, platelet count, plateletcrit, andMPV in the patient group were not statistically different from the control group. Lymphocyte count and PDW weresignificantly higher in patients with HT than in the control group.Conclusion: Our results suggest that patients with HT have higher PDW levels. Increased PDW in HT may be helpful indiagnosis, floow-up, and prognosis of the disease.

Hashimoto tiroiditinin trombositler üzerine sayı, büyüklük ve dağılım açısından etkisi

Amaç: Çalışmamızın amacı, Hashimoto tiroiditi olan hastalarda trombosit endekslerinin etkilenip etkilenmediğini araştırmaktır. Yöntemler: HT'li 11 hasta (10 kadın, 1 erkek) ve kontrol grubu olarak seçilen nodüler guatrlı 26 kişi (19 kadın, 7 erkek) çalışmaya dahil edildi. Tüm olguların tam kan sayımı parametreleri (lökosit sayısı, nötrofil sayısı ve yüzdesi, lenfosit sayısı ve yüzdesi, trombosit sayısı, trombosit yüzdesi, trombosit dağılım genişliği (PDW) ve ortalama trombosit hacmi (MPV)) incelendi. Bulgular: Hasta grubunda lökosit sayısı, nötrofil sayısı ve yüzdesi, lenfosit yüzdesi, trombosit sayısı, platelet yüzdesi ve MPV değerleri kontrol grubundan istatistiksel olarak farklı değildi. Lenfosit sayısı ve PDW, HT'li hastalarda kontrol grubuna göre anlamlı derecede yüksekti. Sonuç: Bulgularımız HT'li hastaların PDW düzeylerinin daha yüksek olduğunu göstermektedir. HT'de artmış PDW, hastalığın tanısı, takibi ve prognozu açısından anlamlı olabilir.

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