Risk factors for intensive care unit need in patients with COVID-19: An analysis of 368 cases

Risk factors for intensive care unit need in patients with COVID-19: An analysis of 368 cases

Objective: Covid-19 is a global epidemic that predominantly affects the respiratory system, in which about 20% of patients are severe and about 10-15% of mild cases become severe. The clinical and laboratory findings in the course of the disease are mild in the first week and may become more severe in the following days, also the possibility false negativity of the tomography in the first 24-48 hours, making it difficult to select patients in triage. Being able to detect cases that may have a serious course in the Covid-19 pandemic will help health systems to function without interruption. In our study, we tried to identify cases that may need intensive care in triage. Methods: Medical records and radiological findings of 368 patients with laboratory-confirmed Severe-Acute-Respiratory-Syndrome Coronavirus-2 infection who were hospitalized between March and June 2020 were reviewed. The patients were analyzed by dividing into two groups; group 1; critically ill patients with severe pneumonia who need intensive care during treatment. Approximately 8% of all patients are in this group. Group 2; non-critical patients who do not need intensive care followed in the clinic. Results: It was determined that the mean age of the patients in Group 1, the rate of being over 50 years old and the male gender ratio were higher than Group 2. Conclusion: Although there are low oxygen saturation, tachypnea and comorbid diseases in critically ill patients in triage, advanced age and male gender were found to be the most important risk factors for intensive care need.

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  • 1.Afzal A. Molecular diagnostic technologies forCOVID-19: Limitations and challenges. J Adv Res. 2020; 26: 149-59.
  • 2.Wu Z, McGoogan JM. Characteristics of andImportant Lessons From the Coronavirus Disease2019 (COVID-19) Outbreak in China: Summary of aReport of 72 314 Cases From the Chinese Center forDisease Control and Prevention 2020; 323(13): 1239-42.
  • 3.Li Q, Guan X, Wu P, Wang X, Zhou L, Tong Y. EarlyTransmission Dynamics in Wuhan, China, of NovelCoronavirus-Infected Pneumonia. N Engl J Med 2020;382: 1199–207.
  • 4.Sethuraman N, Jeremiah SS, Ryo A. InterpretingDiagnostic Tests for SARS-CoV-2. JAMA 2020; 323:2249-51.
  • 5.Mori Y, Notomi T. Loop-mediated isothermalamplification (LAMP): a rapid, accurate, and cost-effective diagnostic method for infectious diseases. JInfect Chemother 2009; 15: 62–9.
  • 6. Procop GW, Brock JE, Reineks EZ, et al. A Comparison of Five SARS-CoV-2 Molecular Assays with ClinicalCorrelations. Am J Clin Pathol.2021; 155(1): 69-78.
  • 7.Xie X, Zhong Z, Zhao W, et al. Chest CT for TypicalCoronavirus Disease 2019 (COVID-19) Pneumonia:Relationship to Negative RT-PCR Testing. Radiology2020; 296(2): E41-E45.
  • 8.Huang P, Liu T, Huang L, et al. Use of Chest CT inCombination with Negative RT-PCR Assay for the 2019 Novel Coronavirus but High Clinical Suspicion.Radiology 2020; 295(1): 22-3.
  • 9.Wang D, Hu B, Hu C, et al. Clinical Characteristics of138 Hospitalized Patients With 2019 NovelCoronavirus-Infected Pneumonia in Wuhan, China.JAMA 2020; 323(11): 1061-9.
  • 10.Chang YC, Yu CJ, Chang SC, et al. Pulmonarysequelae in convalescent patients after severe acuterespiratory syndrome: evaluation with thin-sectionCT. Radiology 2005; 236(3): 1067-75.
  • 11.Chen Y, Liu Q, Guo D. Emerging coronaviruses:Genome structure, replication and pathogenesis. J Med Virol. 2020 92(4): 418-23.
  • 12.Su S, Wong G, Shi W, et al. Epidemiology, geneticrecombination, and pathogenesis of coronaviruses.Trends Microbiol 2016; 24(6): 490 502.
  • 13.Hou W, Zhang W, Ronghua J, et al. Risk factors fordisease progression in hospitalized patients withCOVID-19: a retrospective cohort study. InfectiousDiseases 2020; 0: 1-8.
  • 14.Huang C, Wang Y, Li X, et al. Clinical features ofpatients infected with 2019 novel coronavirus inWuhan, China. Lancet 2020; 395(10223): 497–506.
  • 15.Sun Y, Koh V, Marimuthu K, et al. Epidemiologicaland clinical predictors of COVID-19. Clin Infect Dis2020; 28; 71(15): 786-92.
  • 16.Jain V, Yuan J-M. Predictive symptoms andcomorbidities for severe COVID-19 and intensive careunit admission: a systematic review and meta-analysis.Int J of Public Health 2020; 65(5): 533-46.
  • 17.Arentz M, Yim E, Klaff L, et al. Characteristics andOutcomes of 21 Critically Ill Patients With COVID-19 in Washington State. JAMA 2020; 28; 323(16): 1612-4.
  • 18.Famularo G. Comment on: COVID-19 and OlderAdults: What We Know. J Am Geriatr Soc 2020; 68(10):2197.
  • 19.Chung M, Bernheim A, Mei X, et al (2020) CTimaging features of 2019 novel coronavirus (2019-nCoV). Radiology. 2020; 295(1): 202-207.
  • 20.Ye Z, Zhang Y, Wang Y, Huang Z, Song B. Chest CTmanifestations of new coronavirus disease 2019(COVID-19): a pictorial review. Eur Radiol 2020; 30(8): 4381-9.
  • 21. Özmen C A. The Radiology of COVID-19 Pneumonia. Dicle Med J 2021; 48 (Special Issue): 5-14.
Dicle Tıp Dergisi-Cover
  • ISSN: 1300-2945
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 1963
  • Yayıncı: Cahfer GÜLOĞLU
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