Sinop yöresinde, klinik olarak sağlıklı görülen köpeklerde Ehrlichia canis ve Rickettsia conorii'nin seroepidemiyolojik araştırılması

Amaç. Bu çalışmada, Sinopun köylerinde yaşayan köpeklerde Ehrlichia canis (E. canis) veRickettsia conoriinin (R. conorii) seroprevalansının saptanması ve her iki enfeksiyon etkeniarasındaki ko-seroprevalans oranının ortaya konulması amaçlanmıştır. Yöntem. 2007 Ağustosayında Sinopta klinik olarak sağlıklı görünen 93 köpekten kan örneği alınmış olup, ELISAyöntemiyle E. canis ve R. conorii ile reaktif IgG antikorları araştırılmıştır. Bulgular. Doksan üçköpeğin 17sinde (%18,28) E. canis ve 68inde (%73,12) R. conorii IgG antikor pozitifliğisaptanmıştır. Bir köpekte (%1,08) sadece E. canis, 52 köpekte (%55,91) sadece R. conoriiantikorları saptanmış olup, 16 köpekte (%17,20) ise E. canis ve R. conorii arasında ko- seroprevalans tespit edilmiştir. E. canis veya R. conoriiden birisinin seropozitif olduğu köpekgrubunda diğerinin de seropozitif olma ihtimali yüksek bulunmuştur (Fisher kesin ki-kare testi, p =0,035). Sonuç. Sinop ve benzer iklime sahip yörelerde yaşayan köpekler E. canis ve R. conorienfeksiyonları riski altındadır. Bu doğrultuda, köpeklerin sağlık sorununun çözümünde kenekaynaklı enfeksiyonlar dikkate alınmalıdır. Ayrıca köpek ve insanlar arasındaki dostane yakınlıknedeniyle, E. canis ve R. conoriye karşı köpeklerde görülen antikor pozitifliği, buenfeksiyonların insanlarda da görülebileceğini işaret etmektedir.

The seroepidemiologic survey of Ehrlichia canis and Rickettsia conorii in clinically healthy dogs f rom Sinop region

Aim. The aim of the present study was to determine seroprevalence of Ehrlichia canis andRickettsia conorii in dogs living in the villages of Sinop and to establish co-seroprevalance ratebetween both infection agents. Methods. In August 2007, blood samples were obtained from 93dogs which seemed clinically healthy in Sinop. IgG antibodies to E. canis and R. conorii wereinvestigated in dogs by ELISA. Results. E. canis and R. conorii antibodies were determined in 17(18.28%) and 68 (73.12%) of 93 dogs, respectively. Only E. canis antibodies in 1 (1.08%) of 93dogs and only R. conorii antibodies in 52 (55.91%) of them were determined. And also, the co- seroprevalance between E. canis and R. conorii were determined in 16 (17.20%) of them. In thedog group in which one of R. conorii or E. canis was seropositive, the probability of beingseropositive of other infection agent was high (Fisher's exact test, p = 0.035). Conclusion. Dogsliving in Sinop and somewhere with similar climate are at risk in terms of E. canis and R. conoriinfections. In this respect, tick borne infections should be considered in the solution of dog shealth problems. In addition, because of the friendly relationship between dogs and humans,antibody positivities against E. canis and R. conori in dogs can indicate that these infections can beseen in humans, too.

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