Papillary carcinoma in a thyroglossal duct cyst: Two case reports and review of literature

Tiroglossal duktus kisti, boyun orta hattında en sık görülen konjenital boyun kitlesidir. Tiroglossalduktusun epitelyal kalıntılarından gelişir ve %70 çocuk yaş grubunda %7 ise erişkin yaşlarda tanıalır. Tiroglossal kanal kistinden karsinoma gelişimi oldukça nadirdir. Malignite eksize edilencerrahi spesimenin histolojik incelemesinde tesadüfen saptanır. Tiroglossal kanal kistindekarsinom gelişimi oldukça nadirdir ve olguların %1inden azında gözlenir ve papiller karsinoma(%80) bu kistlerde en sık izlenen malignensidir. Bu çalışmada cerrahi spesmenin histopatolojikincelemesi ile postoperatif dönemde ve preoperatif dönemde ince iğne aspirasyon biopsisi iletiroglossal kist de papiller tiroid karsinomu tanısı almış olan iki olgumuzu sunduk. Erişkin yaşgrubunda tiroglosal kanal kisti tanısı almış olan olgularda preoperatif ince iğne biyopsisi veintraoperatif frozen çalışılması gerektiği kanısındayız.

Tiroglossal kanal kistinde p ap iller karsinoma: İki olgu sunumu ve literatürün gözden geçirilmesi

Thyroglossal duct cysts are the most common form of congenital malformation in the neck. Theydevelop from the epithelial remnants of the thyroglossal tract and 70% is diagnosed in childhood;7% is diagnosed in adulthood. Carcinoma arising in these remnants constitutes a very uncommonhistopathological entity. The diagnosis of malignancy is made incidentally on cytopathologicstudies of the excised surgical specimen. Only 1% of thyroid carcinoma arises from thethyroglossal duct cysts and papillary carcinoma (80%) is the most common malignancy in thiscyst. We describe here two cases of thyroglossal duct cysts. Surgical specimen histopathologystudy showed presence of papillary carcinoma in the first case. Thyroglossal duct cyst waspreoperatively diagnosed via fine needle aspiration biopsy (FNAB) in the second case. We suggestthat in adult cases of thyroglossal duct cysts, fine needle aspiration cytology should be used forpreoperative diagnosis and frozen examination should be done intra operatively.

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