Havva ERDEM, Nilüfer KADIOĞLU, Hakan TURAN, Ümran YILDIRIM, Derya ÖZÇELİK, Cem ŞAHİNER, Ali Kemal UZUNLAR, Murat OKTAY

An aggressive Basal Cell Carcinoma with multiple focuses and distant lung metastasis: case report

Bazal hücreli karsinom (BHK) epidermisin bazal tabakasından kaynaklanan ve nonkeratinizehücrelerden oluşan en yaygın cilt tümörüdür. Dev BHK (yani çapı 5 cmden büyük) oldukçanadirdir ve tüm BHKların %0,5 ini oluşturmaktadır. BHK insidansı yüksek olmasına rağmen, butümörün metastaz oranı tüm vakaların %0,0028-%0,55 arasında değişmektedir. Bu vakada tümördev boyuta ulaştı ve akciğer metastazı vardı. Burada, BHKlar genellikle yavaş seyirli olmasınarağmen gerekli vakalarda yeterli cerrahi ve kemoradyoterapinin önemini vurgulamak istedik.

Multipl odaklı, agresif davranışlı ve uzak metastaz içeren Bazal Hücreli Karsinom

Basal cell carcinoma (BCC) is a malignant neoplasm derived from nonkeratinizing cells thatoriginate from the basal layer of the epidermis and it is the most common type of skin cancer inhumans. Giant BCC (i.e. greater than 5 cm in diameter) is quite rare and comprises 0.5 percent ofall BCC. Despite the high incidence of BCC, metastasis of this tumor is rare, with rates rangingfrom 0.0028% to 0.55% of all BCC cases. In this case, the tumour reached a giant size and had apulmonary metastasis.,We aimed to emphasize that although BCC s are usually indolent; theimportance of adequate surgery and chemoradiotherapy should always be considered in indicatedcases.

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