Mehmet ŞENOĞLU, Mehmet Sait MENZİLCİOĞLU, Betül KIZILDAĞ, Mehmet Fatih İNCİ, Fuat ÖZKAN, Yakup GÜMÜŞALAN

Chiari tip I malformasyonlu hastalarda korpus kallozumun morfometrik ölçümlerinin ve uzaysal oryantasyonunun değerlendirilmesi

Amaç. Bu çalışmada, Chiari tip I malformasyonlu hastalarda korpus kallozumun morfometrikölçümleri ve birtakım açı ölçümleri ile tespit edilen uzaysal oryentasyonunu normal populasyonagöre değerlendirmek amaçlanmıştır. Yöntem. 3-65 yaş arası 28 Chiari tip I malformasyonlu hasta(14 kadın, 14 erkek) ve 41 sağlıklı olgunun, T1 veya T2 ağırlıklı orta sagital kesitli MRgörüntülerinde korpus kallozumun uzunluk, yükseklik, tepe açısı ve uzaysal oryentasyonunubelirleyen 4 farklı açı (A, B, C, D açıları) ölçümü yapıldı. Ölçümler arası farkı belirlemek içinistatistiksel olarak Independent-T testi kullanıldı. Korelasyon için Pearson korelasyon testikullanıldı. Bulgular. Her iki grup karşılaştırıldığında oryentasyon açılarından B ve D açılarındaanlamlı bir fark olduğu bulundu (p0,05).Yaş ile korpus kallozumun uzunluğu ve A açısı arasında pozitif korelasyon saptandı.(sırasıyla r: 0,446 p: 0,043, r: 0,494 p: 0,023). Cinsiyet ile morfometrik ölçümler ve açılar arasındaanlamlı korelasyon saptanmadı. Sonuç. Korpus kallozumun uzaysal oryentasyonu Chiari tip Imalformasyonlu olgularda normal populasyona göre farklılık göstermektedir. Bu sonuçlar, korpuskallozum çalışmalarında uzaysal oryentasyonun önemli bir faktör olabileceğini göstermeklebirlikte daha geniş serilere ihtiyaç vardır.

Evaluation of the morphometric measurement and spatial orientation of corp us callosum in patients with Chiari type I malf ormation

Aim. This study aimed to determine the morphometric measurement and spatial orientation ofcorpus callosum in patients with Chiari type I malformation. Methods. In 28 patients with Chiaritype I malformation (14 women and 14 men) and 41 healthy individuals between the ages of 3-65,length and height of corpus callosum as well as the central angle and four angles (A, B, C, Dangles) to understand the spatial characteristics of the callosum were measured in T1 or T2weighted mid-sagittal MR images. Independent-T test was used to determine the statisticaldifferences between the measurements. Moreover Pearson's coefficient of correlation was used todetermine the correlations. Results. B and D angles of corpus callosum compared between thegroups, had a significant difference (p0.05). There was a positive correlationbetween the age and length of corpus callosum and A angle (r: 0.446 p: 0.043, r: 0.494 p: 0.023,respectively). There was no correlation between gender and morphometric measurements.Conclusion. These results confirm that the spatial orientation of corpus callosum is different fromthe normal population in cases with Chiari Type I malformation. These results suggest that spatialorientation could be an important factor in studies of the corpus callosum, however, further studiesare required with larger sample size.

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