Emine Kılıç BAĞIR, Arbil AÇIKALIN, Elif ÇALIŞ, Serdar ÖZBARLAS, Gülfiliz GÖNLÜŞEN

Multifokal Epiteloid Hemanjioendotelyoma: Olgu Sunumu

Epiteloid hemanjioendotelyoma malign biyolojik davranış sergileyen nadir vasküler bir tümördür. Sıklıkla yumuşak vasküler endotelyal hücrelerden köken alır fakat karaciğer, akciğer, kemik ve deri gibi pek çok lokalizasyonda bulunabilir. Yavaş büyüyen düşük veya borderline malign tümör olarak kabul edilirler ancak agresif formları da bildirilmiştir.Bu yazıda 24 yaşında yumuşak dokuda multifokal yerleşimli epiteloid hemanjioendotelyoma olgusu klınik, radyolojik ve histopatolojik bulguları ile birlikte sunulmuştur.

Anahtar Kelimeler:

epiteloid hemanjioendotelyoma, multifokal, vasküler tümör

Multifocal Epitheloid Hemangioendothelioma: A Case Report

Epitheloid hemangioendothelioma (EHE) is a rare vascular tumor with malignant biological behavior. It arises from vascular endothelial cells, usually within soft tissues, and can occur in almost all locations, but tumor can be found in liver, lungs, bone and skin. It is considered to be a low or borderline malignant tumor with, usually, slow progression, but aggressive forms have been described. We present a 24 year-old female case of multifocal epitheloid hemangioendothelioma of the soft tissue with its clinical, radiological and histopathological findings

Keywords:

epitheloid hemangioendothelioma, multifocal, vascular tumor,

PDF

___

Kerry G, Marx O, Kraus D, et al. Multifocal epithelioid hemangioendothelioma derived from the spine region: case report and literature review. Case Rep Oncol. 2012;5:91-8.
Weiss SW, Enzinger FM. Epithelioid hemangioendothelioma: a vascular tumor often mistaken for a carcinoma. Cancer. 1982; 50:970-981.
Bollinger BK, Laskin WB, Knight CB. Epithelioid hemangioendothelioma with multiple site involvement. Literature review and observations. Cancer. 1994;73:610-5.
Errani C, Sung YS, Zhang L, et al. Monoclonality of multifocal epithelioid hemangioendothelioma of the liver by analysis of WWTR1-CAMTA1 breakpoints. Cancer Genet. 2012;205:12-7.
Madhusudhan KS, Srivastava DN, Gamanagatti S. Multifocal epithelioid hemangioendothelioma presenting with hemoptysis. Indian J Pediatr. 2010;77:699-700.
Deyrup AT, Tighiouart M, Montag AG, et al. Epithelioid hemangioendothelioma of soft tissue: a proposal for risk stratification based on 49 cases. Am j Surg Pathol. 2008;32:924-7.
Weiss SW, Ishak KG, Dail DH, et al. Epithelioid hemangioendothelioma and related lesions. Semin Diagn Pathol. 1986;3:259-87.
Weingartner N, Angelescu M. Multifocal pulmonary and hepatic epithelioid hemangioendothelioma. Rofo. 2005;177:439-40.
Weiss SW, Goldblum JR. Soft tissue tumors. 5 th edition ed, 2008.
Verma SK, Mitchell DG, Bergin D. Case report: MRI diagnosis of multifocal epithelioid hemangioendothelioma of the liver. Indian J Radiol Imaging. 2008;18:239-41.
Errani C, Zhang L, Panicek DM, et al. Epithelioid hemangioma of bone and soft tissue: a reappraisal of a controversial entity. Clin Orthop Relat Res. 2012;470:1498-1506.
Dean PJ, Haggitt RC, O'Hara CJ. Malignant epithelioid hemangioendothelioma of the liver in young women. Relationship to oral contraceptive use. Am J Surg Pathol. 1985;9:695-704.
Yazışma Adresi / Address for Correspondence: Dr. Emine Kılıç Bağır Çukurova Üniversitesi Tıp Fakültesi Patoloji Anabilim Dalı 01330, Balcalı Hastanesi Sarıçam/ADANA Tlf: 0 322 338 6060/3158
Email: eminebagir@yahoo.com geliş tarihi/received :12.08.2013 kabul tarihi/accepted:16.09.2013