İbrahim İnan HARBİYELİ, Elif ERDEM, Anıl UYSAL, Hülya BİNOKAY, Meltem YAĞMUR

Korneanın biyomekanik özelliklerinin farklı glokom tiplerinde Corvis Scheimpflug teknolojisi ile değerlendirilmesi

Amaç: Bu çalışmanın amacı farklı glokom tiplerinde korneanın biyomekanik özelliklerinin incelenmesi ve kornea biyomekaniği ile demografik ve klinik parametreler arasındaki ilişkinin araştırılmasıdır. Gereç ve Yöntem: Bu retrospektif gözlemsel çalışmaya primer açık açılı glokom (PAAG), psödoeksfoliatif glokom (PEG) ve pigmenter glokom (PG) olguları ve kontrol grubu olarak sağlıklı olgular dahil edildi. Tüm olgulara kapsamlı oftalmolojik muayene yapıldı, bilgisayarlı perimetri incelemesi ve optik koherens tomografi (OKT) verileri kaydedildi. Korneal biyomekanik özellikler Corvis ST® (Oculus, Wetzlar, Almanya) ile değerlendirildi. Bulgular: Çalışmaya yaş ortalaması 61,4±11,4 olan 48 glokom olgusu (25 PAAG, 15 PEG, 8 PG; 48 göz) ve 45,2±9,9 olan 51 sağlıklı gönüllü (51 göz) dahil edildi. Birinci aplanasyon hızı (A1V) ve deformasyon amplitüdü (DA) PAAG olgularında diğer gruplara göre daha düşük bulundu. Ayrıca PAAG grubunda 1. aplanasyondaki sertlik parametresi (SP-A1), kontrol grubu ve PEG grubuna kıyasla daha yüksek bulundu. Glokom olgularında, yaş ile stres gerinim indeksi arasında aynı yönlü glokom süresi ile SP-A1 arasında ise ters yönlü bir ilişki bulundu.. Sonuç: Çalışmamızda korneanın PAAG olgularında PEG ve PG olguları ve sağlıklı kornealara kıyasla deformasyona daha dirençli olduğu bulundu. Psödoeksfoliatif glokom ve PG olguları arasında ve bu olgular ile kontrol grubu arasında kornea biyomekaniği açısından bir fark saptanmadı..

Anahtar Kelimeler:

Corvis scheimpflug teknolojisi, kornea biyomekaniği, pigmenter glokom, primer açık açılı glokom, psödoeksfoliatif glokom.

Evaluation of the biomechanical properties of the cornea in different glaucoma types with Corvis Scheimpflug technology

Purpose: The aim of this study was to evaluate the biomechanical properties of the cornea in different types of glaucoma and the relationship between corneal biomechanics and demographic and clinical parameters. Materials and Methods: Primary open-angle glaucoma (POAG), pseudoexfoliative glaucoma (PEG) and pigmentary glaucoma (PG) cases and healthy subjects as a control group were included in this retrospective observational study. Detailed ophthalmological examination was performed, computerized perimetry and optical coherence tomography (OCT) data were recorded in all cases. Corneal biomechanical properties were evaluated with Corvis ST® (Oculus, Wetzlar, Germany). Results: Forty-eight glaucoma cases (25 POAG, 15 PEG, 8 PG; 48 eyes) with a mean age of 61.4±11.4 years and 51 healthy volunteers (51 eyes) with a mean age of 45.2±9.9 years were included in the study. First applanation velocity (A1V) and deformation amplitude (DA) were lower in POAG cases than in other groups. In addition, the stiffness parameter (SP-A1) in the 1st applanation was higher in the POAG group compared to the control and PEG groups.. In glaucoma cases, a positive correlation was found between age and stress strain index, and an inverse relationship between glaucoma duration and SP-A1 Conclusion: The cornea was more resistant to deformation in POAG cases compared to PEG and PG cases and healthy corneas. There was no difference in corneal biomechanics between PEG and PG cases, and between these cases and the control group..

Keywords:

Corneal biomechanics, Corvis scheimpflug technology, pigmentary glaucoma, primary open angle glaucoma, pseudoexfoliative glaucoma,

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