Mehmet ONAY, Aydın Talip YILDOĞAN, Fettah EREN

Migrenli hastalarda başağrısı, korpus kallozum ve derin beyaz madde lezyonları arasındaki ilişki

Amaç: Çalışmanın amacı, beyaz cevher hiperin tensiteleri (BCH) ve korpuskallozum (KK) ölçümlerinin migren özellikleri ile ilişkisini incelemektir. Gereç ve Yöntem: Bu çalışma, 50 migren hastası ve control grubundaki 40 bireyi içeren, vaka-kontrol ve ileriye dönük bir çalışma olarak yapılmıştır. Başağrısının şiddeti ve sıklığı ile başağrısı ağrı özellikleri sorgulandı. Hastalığın etkileri migren özürlülük derecelendirme ölçeği (MIDAS) kullanılarak belirlendi. WMH lezyonları FAZEKAS skalasıiledeğerlendirildi. KK’un morfometrik ölçümleri yapıldı. Ağrı özellikleri ile ölçümler arasındaki ilişki incelendi. Bulgular: Yaş ortalaması 30,86±8,64 (18-51) yıl olan 50 migrenhastası (44 kadın, 6 erkek) vardı. Migren hastalarında çok noktalı BCH'lerin sıklığı control grubuna göre daha yüksekti. İki grup arasında ölçülen KK değerlerinde fark yoktu. Bulantı şikayetleri olan hastalarda BCH'ler daha yaygındı. Fonofobi ve görsel aura semptomları olan hastalarda ölçülen KK genu değerleri dahadüşüktü. Sonuç: Bu çalışma, migrenli hastalarda BCH oranının yüksek olduğunu ve ataklara bulantı eşlik ettiğinde bu oranın daha da yüksek olduğunu ortaya koymuştur. CC'nin ölçülen değerleri ile migren arasında herhangi bir ilişki bulunamadı.

Anahtar Kelimeler:

Migren, manyetik rezonans görüntüleme (MRG), korpus kallozum

Relationship between headache, corpus callosum, and deep white matter lesions in patients with migraine

Purpose: The aim of the study was to examine the relationship of white matter hyperintensities (WMHs) and measurements of corpus callosum (CC) with migraine characteristics. Materials and Methods: This study was conducted as a case-control and prospective study that included 50 migraine patients and 40 individuals in the control group. The severity and frequency of headaches and headache pain characteristics were questioned. The effects of the disease were determined using the migraine disability rating scale (MIDAS). WMH lesions were evaluated with the FAZEKAS scale. Morphometric measurements of CC were performed. The relationship between pain characteristics and measurements was examined. Results: There were 50 migraine patients (44 women, 6 men) with a mean age of 30,86±8,64 (18-51) years. The frequency of multi-point WMHs was higher in migraine patients compared to the control group. There were no differences in the measured values of CC between the two groups. WMHs were more common in patients with nausea complaints. Measured CC genu values were lower in patients with phonophobia and visual aura symptoms. Conclusion: This study has revealed that patients with migraines have a high rate of WMHs, and this rate is even higher when nausea accompanies attacks. No relationships were found between the measured values of CC and migraines.

Keywords:

Migraine, magnetic resonance imagining (MRI), corpus callosum.,

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