Cem AKBAL, Yıloren TANIDIR, Bahadır ŞAHİN, Tarık Emre ŞENER, Deniz FİLİNTE, Leyla CİNEL, İdris ÖNEM, Çağrı AKIN ŞEKERCİ

Jukstaglomerüler Hücreli Tümör (Reninoma): Vaka Sunumu ve Literatür Derlemesi

Reninoma, jukstaglomerüler hücrelerden köken alan nadir bir tümördür. Bu çalışmamızda sekonder hipertansiyon ve yan ağrısı ile üroloji polikliniğine başvuran 17 yaşında bir erkek hastayı ve ardından literatürde reninoma ile ilgili bilgileri sunmayı amaçladık. Hastanın yapılan değerlendirmesinde hipokalemik olduğu görüldü ve çekilen batın manyetik rezonans (MR) görüntülemesinde sağ böbrekte 4.8x4.8 cm’lik kontrast tutan ekzofitik lezyon saptandı. Hastaya açık nefron koruyucu cerrahi operasyon uygulandı ve patolojik inceleme ile eksize edilen lezyonun jukstaglomerüler hücreli tümör (reninoma) olduğu saptandı. Operasyondan kısa bir süre sonra hastanın hipertansiyon tedavisi amacıyla aldığı tüm ilaçlar kesildi ve kan basıncının normal seyrettiği ve hipokaleminin ortadan kalktığı görüldü. Bu vaka, sekonder hipertansiyonun sebeplerinden biri olan reninoma tedavisinin önemini ve tanısal yaklaşımın tedavinin temeli olduğunu gösteren, klinisyenlere yön verebilecek önemli bir vakadır.

Anahtar Kelimeler:

Reninoma, sekonder hipertansiyon, nefron koruyucu cerrahi, tanısal inceleme

Juxtaglomerular Cell Tumor (Reninoma): A Case Report and Mini-Review

Reninomas are rare tumors derived from juxtaglomerular cells. Here, we report a case of a 17-year-old male patient who presented to our outpatient clinic with secondary hypertension and flank pain. Initial work-up revealed hypokalemia, and magnetic resonance imaging (MRI) revealed a solid lesion as a 4.8×4.8-cm contrast-enhanced exophytic mass. He underwent open nephron-sparing surgery, and the lesion was excised. The pathological study revealed a juxtaglomerular cell tumor (reninoma). Shortly after the surgery, all medications were withdrawn, and his blood pressure and hypokalemia normalized. This case can lead physicians to better understand the importance of the management of reninomas as a curable cause of secondary hypertension and also points out the importance of diagnostic care.

Keywords:

Reninoma, secondary hypertension, nephron-sparing surgery, diagnostics,

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