TİROİD KRİZİ İLE PREZENTE OLAN BİR TOKSİK GUATR OLGUSU
Tiroid krizi, nadir görülen ölümcül olabilen bir klinik tablodur. Otuzüç yaşında kadın hasta, hasta- nemize ateş yüksekliği ve bilinç bulanıklığı şikâyetleriyle kabul edildi. Kan tablosunda TSH düşük- lüğü, T3 ve T4 yüksekliği mevcuttu. Fizik muayenede ateş (38,4 °C), taşikardi (130 atım/dk), boyun bölgesinde tiroid bezinde büyüme (+++) ve palpasyonda nodül, akciğerde dinlemekle bilateral ral ve ronküs saptandı. Burch ve Wartofsky skorlamasına göre hastaya tiroid krizi tanısı kondu ve hasta yoğun bakıma yatırıldı. Antitiroid, beta bloker, antibiyotik ve hidrasyon tedavisi başlandı. Birinci haftanın sonunda şuuru ve genel durumu düzelen hasta, antitiroid tedavi ile taburcu edildi.
A Case of Toxic Goiter Presenting with Thyroid Crisis Hafize Kızılkaya , Lütfi Akyol, Asuman Çelikbilek, Murat Suher
Thyroid crisis is a rare clinical condition that can be fatal. Thirty tree years old female patient was admitted to our hospital with complaints of fever and blurred consciousness. There was a decrease in TSH but an increase in T3 and T4 in her blood parameters. Her physical examination revealed fever (38.4 °C), tachycardia (130 beats/min), thyroid gland enlargement (+++) and nodule in palpation in the neck region, bilateral crackles and rhonchi in the chest auscultation. The patient was diagnosed with thyroid crisis according to Burch and Wartofsky scoring and taken to intensive care unit. A treatment of anti-thyroid, beta-blockers, antibiotic and hydration was started. The patient, who gained improvement in consciousness and general condition at the end of the first week, was discharged with antithyroid therapy.
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- 1. Burch HB, Wartofsky L. Life-threatening thyrotoxicosis. Thyroid storm. Endocrinol Metab Clin North Am. 1993; 22(2): 263-77.
- 2. Karger S, Fuhrer D. Thyroid storm-thyrotoxic crisis: an update. Deutsch Med Wochenschr. 2008;133(6): 479-4.
- 3. Akamizu T, Satoh T, Isozaki O, Suzuki A, Wakino S, Iburi T, et al. Diagnostic criteria, clinical features, and incidence of thyroid storm based on nationwide surveys. Thyroid. 2012; 22(7): 661-79.
- 4. Feldt-Rasmussen U, Emerson CH. Further thoughts on the diagnosis and diagnostic criteria for thyroidstorm. Thyroid. 2012; 22(11): 1094-5.
- 5. Wartofsky L. Clinical criteria for the diagnosis of thyroidstorm. Thyroid. 2012; 22(7): 659-60.
- 6. Wald DA, Silver A. Cardiovascular manifestations of thyroidstorm. J Emerg Med. 2003; 25(1): 23-8.
- 7. Akamizu T, Akamizu T1, Satoh T, Isozaki O, Suzuki A, Wakino S, Iburi T, et al. Diagnostic criteria and clinico- epidemiological features of thyroid storm based on a nationwide survey. Thyroid. 2012;3(1):69-73.
- 8. Sarlis NJ, Gourgiotis L. Thyroid emergencies. Rev Endocr Metab Disord. 2003; 4(2): 129-36.
- 9. Jiang YZ, Hutchinson KA, Bartelloni P, Manthous CA. Thyroid storm presenting as multiple organ dysfunction syndrome. Chest. 2000; 118(3): 877-9.
- 10. Ringel MD. Management of hypothyroidism and hyperthyroidism in the intensive care unit. Crit Care Clin. 2001; 17(1): 59-74.
- 11. Wald DA, Silver A. Cardiovascular manifestations of thyroid storm: a case report. J Emerg Med. 2003; 25(1): 23-8.