MYOMA UTERİ TEDAVİSİNDE LAPARASKOPİK UTERİN ARTER KOAGULASYONUN ETKİSİ; VAKA SERİSİ
Amaç: Bu çalışmanın amacı myoma uteri tanısı alan hastalarda laparaskopik bilateral uterin arter koagulasyonunun tedavideki etkisini araştırmaktır. Gereç ve Yöntemler: Haziran 2007-Ekim 2007 tarihleri arasında 29-47 yaş arası myoma uteri tanısı alan semptomatik 10 hastaya laparaskopik bilateral arter koagulasyonu yapıldı. Postopo- peratif myom hacimleri Manyetik Rezonans görüntüleme (MRI) ile değerlendirildi ve hastaların semptomlarındaki değişiklikler kaydedildi. Bulgular: Laparaskopik arter koagulasyonu sonrası anormal uterin kanamaya bağlı semptomlar operasyon öncesine göre % 80 gerilerken kitleye bağlı bası semptomları % 66.6 geriledi. Vakaların myom hacimlerinde ise preoperatif hacimlere göre % 12.5 azalma olduğu MRI ile tespit edildi. Sonuç: Laparaskopik bilateral uterin arter koagulasyonu leiomyomalarda semptomların gerileme- sinde ve myom hacminin küçülmesinde etkilidir bu yüzden histerektomi veya myomektomiye alternatif etkin bir tedavi yöntemi olarak kullanılabilir.
The Efficacy of Laparascopic Uterin Artery Coagulation in the Treatment of Uterin Leiomyoma; Case Series
Objective: The aim of our study is to investigate the efficacy of the laparoscopic uterine artery coagulation in the treatment of patients with the diagnosis uterine leiomyoma. Material and Methods: 10 symptomatic patients with myoma uteri aging between 29-47 years old were taken between June 2007-October 2007 and laparoscopic bilateral artery coagulation was done to patients. Postoperatively, the volumes of myomas were calculated with MRI (magnetic resonance imaging) and the changes of patients symptoms were recorded. Results: After laparoscopic uterine artery coagulation, the abnormal uterine bleeding symptoms reduced % 80 and mass effect reduced % 66.6 when compared preoperative symptoms. In the volume of myomas of cases with MRI 12.5% reduction was recorded when compared preoperative volumes. Conclusion: Laparoscopic bilateral uterine artery coagulation is effective in relieving the myoma uteri symptoms and in reduction of the volume of myoma uteri; so that can be used as an alternative treatment to hysterectomy or myomectomy.
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- 1. Vollenhoven BJ, Lawrence AS, Healy DL. Uterinfibroids. Br J ObstetGynaecol. 1997;97(4):285-98.
- 2. Maruo T, Matsuo H, Shimomuro Y, Kurachi O, Gao Z. Effects of progesterone on gowth factor expression in human uterine leiomyoma. Steroids. 2003;68(10):817-24.
- 3. Hallberg L, Hogdhal A-M, Nilsson L, Rybo G. Menstrual blood loss: a population .Acta Obstet Gynecol Scand. 1966;45(3):320-51.
- 4. Shaw RW. Assesment of medikal treatments for menorrhagia. Br J ObstetGynecol. 1994;101(1): 15-8.
- 5. Farquhan CM, Steiner CA. Hysterectomy rates in the United States 1990-1997. ObstetGynecol. 2002;99(2):229- 34.
- 6. Yen YK, Liu WM, Yunan CC. Laparoscopic bipolar caugulation of uterine vessels to treat symptomatic myomas in women with elevated CA125. J Am Assoc Gynecol Laparosc. 2001;8(2):241-6.
- 7. Burbank F, Hutchins FC. Uterin artery occlusion by embolisation or surgery for the treatment of fibroids. A Unifying hypothesis. Transient uterine ischemia. J Am Assoc Gynecol Laparosc. 2000;7(4):1-49 .
- 8. Liu WM: Ng HT, Wu YC. Laparoscopic bipolar caugulation of uterine vessels: A new method for treating symptomic fibroids. Fertil Steril. 2001;75(2):417-22.
- 9. Linchinter M, Hallson L, Calvo P. Laparoscopic uterine artery occlusion for symptomatic leiomyomas. JAm AssocGynecol Laparosc. 2002;9(2):191-8.
- 10. Park KH, Kim JY, Shin JS, Kwon JY, Koo JS, Jeong KA, et al. Treatment outcomes of uterine artery embolization and laparoscopic uterine artery ligation for uterine myoma. YonseiMed J. 2003;44(4):694-702.
- 11. Helal A, MashalyAel-M, Amer T.Uterin eartery occlusion for treatment of symptomatic uterine myomas. JSLS. 2010;14(3):386-90.
- 12. Stringer NH, Grant T, Park J, Oldham L. Ovarian failure after uterin eartery embolization for treatment of myomas. J Am Assoc Gynecol Laparosc. 2000;7(3):395-400.