Murat TURGAY, Murat VARLI, Ahmet YALÇIN, Sevgi ARAS, Teslime ATLI, Halil İbrahim YILDIZ

GERİATRİK POPÜLASYONDA SERUM D VİTAMİNİ DÜZEYLERİ İLE KEMİK MİNERAL YOĞUNLUĞU ARASINDAKİ İLİŞKİ: ÇAPRAZ KESİTSEL BİR ÇALIŞMA

Amaç: D vitamini eksikliği yaşlı popülasyonda sıkça karşılaşılan bir durumdur. Osteoporoz sıklığı da yaşla beraber artmaktadır ve kalça kırıklarına yol açması nedeni ile önemli bir mortalite ve morbidite nedenidir. Senil osteoporoz özellikle ileri yaşta görülen osteoporoz türüdür ve D vitamini eksikliği ile beraberdir. Çalışmamızın amacı, yaşlı kişilerde D vitamini eksikliği sıklığı ile D vitamin eksikliğinin vertebra ve femur kemik mineral yoğunluklarına (KMY) olan etkisini araştırmaktır. Gereç ve Yöntemler: Çalışmaya Ankara Üniversitesi Tıp Fakültesi Cebeci Hastanesi Geriatri Bilim Dalı polikliniklerine başvuran toplam 213 yaşlı kişi katıldı. Katılımcıların serum D vitamini, kalsiyum, fosfor, alkalen fosfataz düzeyleri, ultraviyoleden yararlanma oranları ve KMY değerleri ölçüldü. D vitamini eksikliği serum 25 hidroksi vitamin D3düzeyi0,05) hem de vertebra KMY (r=0,029,p>0,05) değerleri arasında anlamlı korelasyon saptanmadı.Sonuç: Geriatrik popülasyonda D vitamini eksikliği sıklığı çalışmamızda yüksek saptanmıştır. D vitamini eksikliğine parathormon yüksekliği eşlik etmektedir. Literatürün aksine D vitamini eksikliği ile femur ve vertebra KMY değerleri arasında ilişki saptanmamıştır. Bunun nedeni yaşlıların D vitamini düzeylerine tüm yıl içerisinde bakılmış olması olabilir.

The Relationship Between Serum Vitamin D Levels and Bone Mineral Density Among Geriatric Population: A Cross Sectional Study

Objective: Vitamin D insufficiency is a common condition among older people. The prevalence of osteoporosis is also increasing with aging. Osteoporosis is an important cause of mortality and morbidity because of increased fracture risk. Senile osteoporosis, which is seen especially in older population, usually accompanies vitamin D insufficiency. The aim of our study is to evaulate the prevalence of vitamin D inssuficiency among older people and the effect of vitamin D insufficiency on bone mineral density (BMD). Material and Methods: Totally 213 older individuals who were admitted to Geriatric Medicine Department of Ankara University School of Medicine participated in the study. Serum vitamin D, calcium, phosphor, alkaline phosphatase, BMD and ultraviolet exposure levels were measured.25 hydroxyvitamin D3 level0.05).Conclusion: The prevalence of vitamin D insufficiency was found high among older people in our study. Vitamin D insufficiency was concomitant with high parathyroid hormone levels. Contrary to literature, there was no correlation with femur and vertebrae BMD and vitamin D levels. The reason for this might be the measurement of vitamin D levels throughout all year.

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