Özhan PAZARCI, Volkan GÜNEYLİ, Seyran KILINÇ, Zekeriya ÖZTEMUR, Seyfi Gündüz TEZEREN, Okay BULUT, Hayati ÖZTÜRK

ARTER TAMİRİNDE N-BUTİL-2-SİYANOAKRİLAT (HİSTOAKRİL) KULLANIMI

Amaç: Siyanoakrilat birçok cerrahi alanda başarıyla kullanılmakta olup, son yıllarda mikrovaskü-ler anastomoz amacıyla kullanılmaya başlanmıştır. Çalışmamızın amacı geleneksel sütür tekniğiile kendi geliştirdiğimiz siyanoakrilat ile güçlendirilmiş sütür tekniğini karşılaştırmaktır.Gereç ve Yöntemler: Çalışmaya toplam 16 Yeni Zelanda türü tavşan alındı. 8 Tavşan kontrol gru-buna, 8 tavşan ise çalışma grubuna dâhil edildi. Sol femoral arterleri hazırlanarak, tam kat ke-sildi. Kontrol grubunda 90° acı ile dört sutur konularak geleneksel anastomoz uygulandı. Deneygrubunda ise ön yüze tek sütür konulup, arka yüzde proksimal parça distalin içine geçirilip, siya-noakrilat damlatılarak anastomoz uygulandı. Klinik değerlendirme ve istatistik analiz yapılarak,operasyon süresi, kanama süresi ve geciş incelendi.Sonuçlar: Anastomoz iyileşmesi, 21. günde tavşanların sakrifiye edilerek alınan biyopsilerin ışıkmikroskopisi altında histolojik olarak incelenmesi ile değerlendirildi. İki grup arasında lümençapları açısından anlamlı fark vardı. Deney grubunda operasyon ve kanama süreleri anlamlı ola-rak kısa bulundu. Daha fazla endotel kaybı ve inflamasyon görülmesine rağmen akım engelle-miyordu.Çıkarım: Uyguladığımız yöntem basit, az sütürle, kısa zamanda gerçekleştirilen, geçiş oranınıazaltmayan, bir teknik olarak değerlendirilmiştir.

The Using of N-butyl-2-cyanoacrylate (Histoacryl) at Artery Mending

Objective: Cyanoacrylate has been successfully used in many surgical fields and it has been also used for microvascular anastomosis in recent years. The purpose of this study is to compare the traditional suture technique with the enhanced cyanoacrylate suture technique that we have developed. Material and Methods: 16 New Zeland rabbits has researched included in this study. Control group includes 8 rabbits and study group includes 8 rabbits. Left femoral arteries were prepared and cut into full layers. Traditional anastomosis was performed by placing four sutures with 90 ° angle in the control group. But the testing group, the anastomosis is applied by putting one suture to the front part, by putting a proximal item in distal at back part and by putting cyanoacrylate in it. Clinical evaluation and statistical analysis were researched, the operation and duration of bleeding with vessel passage were investigated. Results: On day 21, anastomosis healing was histologically examined under light microscopy of the sacrificed rabbits and the results were evaluated. There was a significant difference between the two groups in terms of luminal diameters. Operation and bleeding time is found short at testing group. although there was more endothelial loss and inflammation in the experimental group, blood flow was not prevented. Conclusion: it can be evaluated easy methods what we used, it can be evaluated as a technique that is performed in a short time and does not decrease the blood transit ratio. We think that, there is need to new studies and pratic applications about these subjects.

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