Flavonoidlerin Kanser Gelişimi ve Seyri Üzerine Etkileri

Flavonoidler, bitkileri zararlı etkenlere karşı koruyan biyoaktif bileşenlerdir. Sebze, meyve ve tahıllarda bol miktarda bulunan flavonoidlerin; antiinflamatuar, antioksidan, antidiyabetik, antihipertansif, antimikrobiyal olmak üzere birçok önemli özelliklere sahip oldukları saptanmıştır. Bu özellikleri nedeniyle flavonoidler, kanser başta olmak üzere kardiyovasküler hastalıklar, diyabet, obezite gibi bulaşıcı olmayan kronik hastalıkların önlenmesinde ve tedavisinde önem taşımaktadır. Son yıllarda doğal bitkisel tedavilere artan talep ve kansere bağlı ölümlerin artması ile birlikte flavonoidlerin kanser üzerindeki etkileri çalışmalarda sıklıkla araştırılan bir konu haline gelmiştir. Bu derlemede, flavonoidlerin kanser gelişimi ve seyri üzerindeki etkilerini ele alan çalışmalar incelenmiştir.

Anahtar Kelimeler:

Flavonoidler, kanser, antioksidan, oksidatif stres

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