D Vitamini Eksikliği ve Obezite İlişkisi

Obezite, günümüzün en yaygın sağlık sorunlarından olup tüm dünyayı etkilemektedir. Obezite, kardiyovasküler hastalıklar, kanser türleri, diyabet gibi birçok hastalık ile de ilişkili bulunmuştur. D vitamini, vücutta endojen olarak sentezlenen bir vitamin olup kemik dokusunun korunması, kalsiyum-fosfor homeostazının sağlanması gibi birçok görevde rol oynamaktadır. D vitamini eksikliği, güneş ışığına yeterince maruz kalmama, yetersiz beslenme gibi birçok faktöre bağlı olarak yaygın görülmektedir. D vitamini eksikliği kardiyovasküler hastalıklar, arteriyel hipertansiyon, dislipidemi, tip 2 diyabet, kanser, multipl skleroz, depresyon, demans, psikiyatrik hastalıklar ve diğerleri gibi çok sayıda bozuklukla ilişkilendirilmiştir. Obezitenin patogenezinde D vitamini eksikliğinin rolünü düşündüren çeşitli hipotezler gelişmiştir. Genel olarak çalışmalarda obezite ve serum D vitamini düzeyleri arasında ters bir ilişki olduğu bildirilmiştir.

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