Follow-up criteria and cystoscopic classifications of bladder lesions: A retrospective analysis
Follow-up criteria and cystoscopic classifications of bladder lesions: A retrospective analysis
Aim: To screen cystoscopically bladder cancer mimicking lesions and to present its clinical importance.Material and Methods: After receiving anamnesis of patients, hematological, biochemical, microbiological, cytological, pathologicand radiological assessments were performed. Randomized cold cup bladder biopsy, transurethral resection or open surgicalexcision were performed. The lesions were classified according to their cystoscopy appearance. Practical approach criterias werecompiled based on their treatments and follow-up, throughout 9 years.Results: A total of 297 patients were reached .The mean age of all were 62±6 years. Almost all bladder lesions (95 %) were prediagnosed as bladder cancer according to the radiologic screening results like bladder wall thickening and irregularities. Theprecancerous /cancerous lesions were detected incidentally at a rate of 3.36 %. PAP (Papanicolaou) III urine cytology was observed ata rate of 3.4 %. Carcinoma in situ developed in the follow-ups and one converted to Grade I transitional cell cancer. Total cystectomywas required in a patient who was diagnosed with urinary tuberculosis.Conclusions: There may be precancerous or cancerous lesions in the background of these lesions which do not respond to treatmentor constantly recur. There may be changes in favor of malignancies in lesions. The study created a different perspective on theselesions with cystoscopy classification.
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- 1. Wein AJ, Kavoussi LR, Partin AW, et al. Bladder Lesions, Wein AJ, Kavoussi LR, Partin AW eds.Campbell-Walsh Urology Philadelphia: Elseveir 2016;3:2184-90.
- 2. Sauter G, Amin AF, Busch C, et al. Noninvasive urothelial neoplasias: WHO classification of noninvasive papillary urothelial tumors. In: Eble J, Epstein J, Sesterhenn I, eds. World Health Organization classification of tumors: pathology and genetics of tumors of the urinary system and male genital organs. Lyon (France): IARC Press 2004;110.
- 3. Koss LG. Tumors of the urinary tract and prostate. In: Koss LG eds. Diagnostic Cytology and its histopathologic bases. 5th edition. Philadelphia: JB Lippincott 2005;810-6.
- 4. Tomkova K, Tomka M, Zajac V. Contribution of p53, p63, and p73 to Developmental Diseases and Cancer. Neoplasma 2008;55:177-81.
- 5. Reddy Y, Hirose R, Lubet V, et al. Chemoprevention of colon cancer by specific cyclooxygenase-2 inhibitor, celecoxib, administered during different stages of carcinogenesis. Cancer Res 2000;293-7
- 6. Semins MJ, Schoenberg MP. A case of florid cystitis glandularis. Nat Clin Pract Urol 2007;4:341–5.
- 7. Sparks S, Kaplan A, DeCambre M, et al. Eosinophilic cystitis in the pediatric population: a case series and review of the literature. J Pediatr Urol 2013;9:738-44.
- 8. Tsakiri A, Balslev I, Klarskov P. Eosinophilic cystitis induced by penicillin. Int Urol Nephrol 2004;36:159- 61.
- 9. Knüchel-Clarke R, Gaisa NT. Preneoplastic lesions and precursors of urothelial cancer. Pathologe 2016;37:33-9.
- 10. Marcon J, Stief CG, Magistro G. Urinary tract infections: What has been confirmed in therapy? Internist (Berl) 2017;58:1242-9.
- 11. Stimac G, Dimanovski J, Katusic J, et al. A large cavernous hemangioma of the urinary bladder: imaging of possible spontaneous regression. Eur J Radiol Extra 2007;61:61-3.
- 12. De Sousa CSM, Viana IL, de Miranda CLVM, et al. Hemangioma of the urinary bladder:an atypical location. Radiol Bras 2017;50:271-2 .
- 13. Hurst RE, Meerveld BG, Wisniewski AB, et al. Increased bladder permeability in interstitial cystitis/painful bladder syndrome. Transl Androl Urol 2015;4:563-71.
- 14. Altiparmak MR, Yalin SF, Denizli N, et al. Urinary tuberculosis: a cohort of 79 adult cases. Ren Fail 2015;37:1157-63.
- 15. Robert H Young. Tumor-like lesions of the urinary bladder. Modern Pathology 2009;22:37-52.
- 16. Ozbey I, Aksoy Y, Polat O, et al. Squamous metaplasia of the bladder: findings in 14 patients and review of the literature. Int Urol Nephrol 1999;31:457-61.
- 17. Harik LR, O'Toole KM. Nonneoplastic lesions of the prostate and bladder. Arch Pathol Lab Med 2012 ;136:721-34.
- 18. Ong C, Lee VK, Mohamed Suphan N, et al. Xanthogranulomatous cystitis: A case report and clinicopathological review. Ann Acad Med Singapore 2013;42:301-3.
- 19. Lane Z, Epstein JI. Polypoid/papillary cystitis: A series of 41 cases misdiagnosed as papillary urothelialneoplasia.Am J Surg Pathol 2008;32:758- 64.