Hüseyin Fatih GÜL, Nail AKSOY, Turgut DOLANBAY, Murat ARAS

Evaluation of non-surgical methods in treatment of pediatric liver cyst hydatid

Aim: Hydatid cyst is a zoonotic infestation caused by helminthes of the Echinococcus genus and humans are intermediate hostsinfected with the contaminated fresh food or water. The cases in Turkey are confined to Eastern Anatolia region. Evaluating theprevalence, symptoms and signs of hydatid cysts along with the treatment procedures and response in pediatric cases are vital forbetter diagnostic and treatment approaches in children.Material and Methods: The study was conducted retrospectively with a total of 27 children diagnosed with hydatid cyst admitted toResearch and Education Hospital of Kafkas University Medical School, Turkey in 2016 and 2019.Results: The mean age of 27 cases reported here was 11.59±4.95. Liver involvement was observed in all of patients reported hereand all patients were seropositive. Ten patients underwent Puncture Aspiration Injection Re-aspiration procedure and 17 patientsdid not undergo. After the Puncture Aspiration Injection Re-aspiration treatment, there was an improvement in all patients for themarker levels.Conclusion: We think that Puncture Aspiration Injection Re-aspiration is superior to non-surgical medical treatment in pediatricpatients.

PDF

___

1. Eckert J, Deplazes P. Biological, epidemiological, and clinical aspects of echinococcosis, a zoonosis of increasing concern. Clin Microbiol Rev 2004;17:107- 35.
2. Özcel MA, Özbel Y, Ak M. Özcel’in tıbbi parazit hastalıkları. Türkiye Parazitoloji Derneği; 2007.
3. Munzer D. New perspectives in the diagnosis of echinococcus disease. J Clin Gastroenterol 1991;13:415-23.
4. Romig T. Epidemiology of echinococcosis. Langenbecks Arch Surg 2003;388:209-17.
5. Sayek İ. Temel Cerrahi 3 baskı. Ankara Güneş Kitabevi. 2004;157:1503-22.
6. Saygı G. Hydatidosis in Turkey within the last fourteen years (1979-1993). Cumhuriyet Üniversitesi; 1996.
7. Moro P, Schantz PM. Echinococcosis: A review. Int J Infect Dis 2009;13:125-33.
8. Demirhan R. Surgical treatment of giant hydatid cysts in childhood. Turkish J Thoracic and Cardiovascular Surg 2010;18.
9. Parelkar SV, Gupta RK, Shah H, et al. Experience with video-assisted thoracoscopic removal of pulmonary hydatid cysts in children. J Pediatr Surg 2009;44:836- 41.
10. Kabaalioglu A, Ceken K, Alimoglu E, et al. Percutaneous imaging-guided treatment of hydatid liver cysts: do long-term results make it a first choice? Eur J Radiol 2006;59:65-73.
11. Brunetti E, Kern P, Vuitton DA. Expert consensus for the diagnosis and treatment of cystic and alveolar echinococcosis in humans. Acta Tropica 2010;114:1- 16.
12. Gargouri M, Amor NB, Chehida FB, et al. Percutaneous treatment of hydatid cysts (Echinococcus granulosus). Cardiovasc Intervent Radiol 1990;13:169-73.
13. Gavara CG, López-Andújar R, Ibáñez TB, et al. Review of the treatment of liver hydatid cysts.WJG 2015;21:124.
14. Manterola C, Otzen T. Surgical Alternatives Used in the Treatment of Liver Hydatid Cyst. A Systematized Approach Based on Evidence (an Overview). Int J Morphol 2016;34.
15. Eren S, Kantarcı M. Perkütan Karaciğer Kist Hidatik Tedavisi. Trd Sem 2015;3:227-36.
16. Teggi A, Lastilla MG, De Rosa F. Therapy of human hydatid disease with mebendazole and albendazole. Antimicrob Agents Chemother 1993;37:1679-84.
17. Senyuz OF, Yesildag E, Celayir S. Albendazole therapy in the treatment of hydatid liver disease. Surgery Today 2001;31:487-91.
18. El-On J. Benzimidazole treatment of cystic echinococcosis. Acta Tropica 2003;85:243-52.
19. Chen X, Cen C, Xie H, et al. The comparison of 2 new promising weapons for the treatment of hydatid cyst disease: PAIR and laparoscopic therapy. Surgical Laparoscopy, Endoscopy & Percutaneous Techniques 2015;25:358-62.
20. Eckert J, Gemmell MA, Meslin F-X, et al. WHO/OIE manual on echinococcosis in humans and animals: a public health problem of global concern. 2001;
21. Gharbi HA, Hassine W, Brauner MW, et al. Ultrasound examination of the hydatic liver. Radiology 1981;139:459-63.
22. Tevfik M, Aldemir OS, Karadaş K, ve ark. Malatya bölgesinde uniloküler kistik ekinokokkozis. Türkiye Parazitol Derg 2000;24:33-6.
23. Craig PS, Rogan MT, Campos-Ponce M. Echinococcosis: disease, detection and transmission. Parasitology 2003;127:5-20.
24. Altıntaş N, Yazar S, Yolasığmaz A, ve ark. Türkiye’de 1980-1998 yılları arasında saptanan alveolar echinococcosis olguları. T Parazitol Derg 1999;23:133- 6.
25. Dashti AS, Kadivar MR, Alborzi A, et al. Analysis of hospital records of children with hydatid cyst in south of Iran. J Parasit Dis 2017;41:1044-8.
26. Kılıç S, Babür C, Taylan Özkan A. Kist hidatik ön tanılı olgularda İndirek Hemaglütinasyon ve ELISA yöntemleri ile alınan sonuçların karşılaştırılması. Mikrobiyoloji Bülteni 2007;41:571-7.
27. Gulsun S, Cakabay B, Kandemır MN, et al. Retrospective analysis of echinococcosis in an endemic region of Turkey, a review of 193 cases. Iran J Parasitol 2010;5:20.
28. Akhan O, Ozmen MN, Dincer A, et al. Liver hydatid disease: long-term results of percutaneous treatment. Radiology 1996;198:259-64.
29. Pekcici MR, Canlı AB, Uyanık İ, et al. Abdominal kist hidatik olgularımızın retrospektif değerlendirilmesi. Tıp Araştırmaları Dergisi 2004;1:5-10.
30. Chai J, Wei J, Deyu S, et al. Observations on clinical efficacy of albendazole emulsion in 264 cases of hepatic cystic echinococcosis. Parasitol Int 2004;53:3-10.
31. Yetim I, Erzurumlu K. Karaciğer hidatik kistleri tedavisinde güncel yaklaşımlar. J Clin Anal Med 2013;4:64-71.