Erkin PEKMEZCİ

Long duration single pulse intense pulsed light application in erythematotelangiectatic rosacea: An instrumental retrospective study

Aim: Erythematotelangiectatic rosacea is a challenging condition due to poor therapeutic options. Treatment with intense pulsedlight is partially effective after numerous sessions. Regarding the ‘thermal relaxation time’ principle and characteristic histopathologyof erythematotelangiectatic rosacea, dilated capillaries and venules throughout the dermis, we proposed that directly targeting thelargest vessels available by applying a long duration single pulse intense pulsed light mode, should decrease the mean number oftreatment sessions to obtain a significant outcome.Material and Methods: Eighty seven erythematotelangiectatic rosacea patients who completed the proposed one month apart,four times consequtive intense pulsed light treatments with 25 ms pulse duration, single pulse and 10 J/cm2 fluence in the yearsof 2017-2019 were recruited retrospectively. Instrumental evaluations and self-assessment scorings were performed during thetreatment period.Results: No adverse effect was recorded. Instrumentally evaluated results revealed a significant erythema quenching effect obtainedat the end of 2nd treatment session (p=0.0011). Considering the decrease in erythema, both the instrumental and self-assessmentvalues were found extremely significant after the 4th session, compared to initial values (p

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1. Lim HS, Lee SC, Won YH, et al. The efficacy of intense pulsed light for treating erythematotelangiectatic rosacea is related to severity and age. Ann Dermatol 2014;26:491-5.
2. Saghari S, Keri J, Shanler S, et al. Rosacea (type 2 sensitive skin). In: Bauman L, ed. Cosmetic Dermatology. 2nd edition. New York: McGrawHill 2009;128-32.
3. Weinkle AP, Doktor V, Emer J. Update on the management of rosacea. Clin Cosmet Investig Dermatol 2015;8:159-77.
4. Lee WJ, Lee YJ, Lee MH, et al. Prognosis of 234 rosacea patients according to clinical subtype: the significance of central facial erythema in the prognosis of rosacea. J Dermatol 2016;43:526-31.
5. Hoffmann MA, Lehmann P. Physical modalities for the treatment of rosacea. J Dtsch Dermatol Ges 2016;14::38-43.
6. Micali G, Gerber PA, Lacarrubba F, et al. Improving treatment of erythematotelangiectatic rosacea with laser and/or topical therapy through enhanced discrimination of its clinical features. J Clin Aesthet Dermatol 2016;9:30-9.
7. Kaufman J. Lasers and light devices. In: Bauman L, ed. Cosmetic Dermatology. 2nd edition. New York: McGrawHill 2009;212-20.
8. 8. Vallee JA, Kelly KM, Rohrer TE, Arndt KA, Dover JS. Lasers in the treatment of vascular lesions. In: Kaminer MS, Arndt KA, Dover JS, Rohrer TE, Zachary CB, eds. Atlas of Cosmetic Surgery. 2nd edition. Philadelphia: Saunders Elsevier 2009.p.135-53.
9. Rohrer TE, Ort RJ, Arndt KA, et al. Lasers in the treatment of pigmented lesions. In: Kaminer MS, Arndt KA, Dover JS, Rohrer TE, Zachary CB, eds. Atlas of Cosmetic Surgery. 2nd edition. Philadelphia: Saunders Elsevier 2009;155-77.
10. Husain Z, Alster TS. The role of lasers and intense pulsed light technology in dermatology. Clin Cosmet Investig Dermatol 2016;9:29-40.
11. Goldberg DJ. Current trends in intense pulsed light. J Clin Aesthet Dermatol 2012;5:45-53.
12. Patil UA, Dhami LD. Overview of lasers. Indian J Plast Surg 2008;41:101-13.
13. Wat H, Wu DC, Rao J, et al. Application of intense pulsed light in the treatment of dermatologic disease: a systematic review. Dematol Surg 2014;40:359-77.
14. Schroeter CA, Haaf-von Below S, Neumann HA. Effective treatment of rosacea using intense pulsed light systems. Dermatol Surg 2005;31:1285-9.
15. Kassir R, Kolluru A, Kassir M. Intense pulsed light for the treatment of rosacea and telangiectasias. J Cosmet Laser Ther 2011;13:216-22.
16. Campolmi P, Bonan P, Cannarozzo G, et al. Intense pulsed light in the treatment of non-aesthetic facial and neck vascular lesions of 85 cases. J Eur Acad Dermatol Venereol 2011;25:68-73.