AYTEKİN ÇIKMAN, MEHMET PARLAK, HÜSEYİN GÜDÜCÜOĞLU, Mustafa BERKTAŞ

Van yöresinde Helicobacter pylori prevalansı, yaş ve cinsiyete göre dağılımı

Çalışmada dışkı antijen testi istemi ile laboratuvarımıza gönderilen taze dışkı örneklerinde, H.pylori antijen prevalan sı ile yaş ve cinsiyete göre dağılımının belirlenmesi amaçlanmıştır. Ocak 2006-Aralık 2010 tarihleri arasında 8402 farklı hastaya ait dışkı örneğinin sonuçları geriye dönük olarak araştırıl mış, her hasta için yalnızca ilk örneğin sonucu çalışmaya dahil edilmiştir. H.pylori dışkı antijen pozitifliğinin yaş, çocuk-erişkin grupları ve cinsiyetlere göre farkın istatistiksel açıdan belirlenebilmesi için Z testi ile oran karşılaştırılması yapılmıştır. İncelenen dışkı örneklerinin 4304ü (% 51) çocuk ve 4098i (% 49) erişkin hastalara aitti. H.pylori antijen pozitiflik oranı çocuk grubunda % 20.7, erişkinlerde % 25.5 olmak üzere toplamda % 23 olarak belirlenmiştir. Erişkin hastalarda daha yüksek oranda görülen bu fark istatistik olarak da anlamlı bulunmuştur (p

Anahtar Kelimeler:

Dışkı, Yaygınlık, Helicobacter pylori, Yaş dağılımı, Cinsiyet dağılımı

The age and gender distribution of Helicobacter pylori prevalence in Van region

In this study, we aimed to determine the prevalence of H. pylori antigens and distribution according to age and gender groups in fresh stool samples sent to our laboratory with stool antigen test request. Results of 8402 stool specimens obtained from different patients and sent to the laboratory with H.pylori stool antigen test request between January 2006 and December 2010, were retrospectively evaluated. For each patient, only the first result was included in the study. Statistical differences between H.pylori stool antigen positivity rates in different age, gender and child-adult groups were determined using Z proportion test. 4304 (51 %) of examined stool samples belonged to children and 4098 (49 %) to adult patients. Positivity rates of H.pylori antigen in children, adults group and in total were 20.7 %, 25.5 % and 23 %, respectively. Higher rate seen in adult patients compared to children group was found statistically significant (p<0.001). Whereas statistically significant difference between genders in children group was not observed, in adult group womens H.pylori positivity rate was found significantly higher (p<0.05). H.pylori antigen frequencies distribution by age groups showed increase in H. pylori antigen prevalence parallel to age increase, with the highest values in 26-35 age group, drawing a plateau in the subsequent age groups and showing decrease in group above 56 years. As a result, the high prevalence of H. pylori and increase of prevalence parallel to age are significant facts. Commonly seen bacterium H.pylori with its well known relationship with gastric cancer and required eradication after diagnosis, is a major public health problem in our region.

Keywords:

Feces, Prevalence, Helicobacter pylori, Age Distribution, Sex Distribution,

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