Antimikrobiyal direnç ve önleme politikaları

Antibiyotiklere karşı direnç artışı ciddi morbidite ve mortaliteye neden olmaktadır. Antibiyotik direncinin gelişiminde ve ortaya çıkmasında rol oynayan faktörler; antibiyotik kullanımı, infeksiyon kontrolü yetersizliği ve çevredir. Antibiyotik tedavi sürelerinin optimizasyonu da direncin önlenmesinde çok önemlidir. Son yıllarda prokalsitonin ile yapılan çalışmalar tedavi sürelerinin optimizasyonunda gelecek için ümit taşımaktadır. Antibiyotik direnci, hasta güvenliği ve maliyet problemi antibiyotik kullanımının yönetimine olan gereksinimi gündeme getirmektedir. Antibiyotik kullanımının yönetimi; multidisipliner, programlı ve ileriye dönük müdaheleleri içeren bir yapıda olmalıdır.

Antimicrobial resistance and prevention policies

The increase of antibiotic resistance causes severe morbidity and mortality. The factors that play roles for the development and emergence of antibiotic resistance includes usage of antibiotics, infection control insufficiency and environment. Optimization of treatment duration is very important for prevention of resistance. Procalcitonin studies which was conducted in recent years carries hope for future in the optimization of treatment duration. Antibiotic resistance, patient safety and cost problems indicate the need of antibiotic stewardship programmes. Antibiotic stewardship programme should include multidiciplinary structure, programmatic and prospective interventions.

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