Primer beyin tümörlerini evrelendirmesinde perfüzyon MRG’nin katkısı

Amaç: Primer malign lezyonlarda farklı histopatolojik tiplerdeki beyin tümörlerinde serebral kan hacminde (CBV) istatiksel açıdan anlamlı fark bulunup bulunmadığını saptamak. Ayrıca bu ölçümlerin tümör derecesi ile bağlantılı olup olmadığını da araştırdık. Gereç ve Yöntem: Bu çalışmaya primer beyin tümörü saptanan 25 hasta (20’si erkek, 5’i kadın) dahil edildi. MRG incelemeleri 1.5 T süperiletken magnet ile standart kafa sarmalı kullanılarak yapıldı. Tüm hastalara konvansiyonel MRG ve dinamik kontrastlı perfüzyon MRG aynı seansta yapıldı. Tespit edilen lezyon alanlarında rCBV oranları hesaplandı. rCBV oranını hesaplarken standart referans olarak kullanılmak üzere transaksiyel planda işaretlenen patolojik alanın karşı tarafında, aynı piksel sayısında alan işaretlenmiştir. Karşılaştırma amacı ile örnek alınan standart referans bölgeler; konvansiyonel T1A ve T2A kesitlerde normal sinyal özellikleri dikkate alınarak seçilmiştir. Bulgular: İncelenen tümörlerden 16’si yüksek evreli glial tümör (YEGT), 9’u düşük evreli glial tümör (DEGT) üdü. Tümöral rCBV ölçümlerine göre DEGT olguları ile YEGT (p

Contribution of perfusion MRI at staging primary brain tumors

Purpose: To determine whether there are statistically differences in cerebral blood volume (CBV) of brain tumors of different histopathological types including primary malignant lesions. To determine whether these measurements relate to tumor grade. Materials and Methods: Our study included 25 patients (20 male, 5 female) who have primary intracranial tumors. MRI was performed in a 1.5 T, superconductive magnet with standart head coils. Conventional MRI and dynamic contrast-enhanced MRI were both performed at same time on all patients. rCBV ratios were calculated in and around the lesions detected while an area of the same pixel number and the opposite side of the pathologic area was pointed as a standart reference in the transaxial plane. Standart reference area chosen for a comparison had normal signal characteristics in the T1W and T2W images. Results: Sixteen of all tumors were high-grade glial tumors (HGGT), and nine were low-grade glial tumors (LGGT). Statistically meaningful differences were detected between HGGT and LGGT (p

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