Fatma YÜLEK, Bekir ÇAKIR, Didem ÖZDEMİR, Ayşe Güzin TAŞLIPINAR, Elif İnci ERBAHÇECİ TİMUR, Reyhan ERSOY, Nagihan UĞURLU

Diyabetik Retinopatisi Olmayan Tip 1 Diyabet Olgularında Retinal Mikrovasküler Yapıların İncelenmesi

Amaç: Sunulan çalışmanın amacı retinopati tespit edilmemiş tip 1 diyabet olgularında, optik koherenstomografi anjiyografi (OCTA) bulgularının değerlendirilmesidir.Materyal ve Metot: Çalışmaya 11 tip 1 diyabet olgusunun 17 gözü ve 18 sağlıklı gönüllü olgunun 36 gözüdahil edildi. Optik koherens tomografi anjiyografi görüntüleri, mikrovasküler değişikliklerin varlığıaçısından değerlendirildi ve yüzeysel kapiller pleksus (SKP) ve derin kapiller pleksus (DKP) seviyelerindefoveal avasküler zone (FAZ) alanı ve vasküler densite (VD) ölçümleri yapıldı.Bulgular: Optik Koherens Tomografi Anjiyografi incelemelerinde, 11 tip 1 diyabet olgusunun 7’sindemikrovasküler değişiklikler izlendi. Diyabetik grup ve kontrol grubu arasında SKP ve DKP seviyelerindeyapılan faz ölçümlerinde anlamlı bir fark izlenmedi (sırasıyla p=0,647, p=0,874). Diyabetik grup ve kontrolgrubu arasında SKP ve DKP seviyelerinde yapılan VD ölçümleri arasında da anlamlı bir fark yoktu (p>0,05).Sonuç: Klinik olarak diyabetik retinopati tanısı almamış diyabetik olgularda, retinal mikrovasküler yapıdaharabiyet gelişebilir. Optik koherens tomografi anjiyografi, erken evrede gelişen mikrovasküler bulgularıntanınmasında faydalı olan, hızlı, girişimsel olmayan ve güvenli bir görüntüleme yöntemidir.

Evaluation of Retinal Microvascular Structures in Type 1 Diabetic Patients without Diabetic Retinopathy

Objectives: The aim of the present study is to evaluate the optical coherence tomography angiography (OCTA) images in patients with type 1 diabetes who have not been diagnosed with retinopathy. Materials and Methods: The study included 17 eyes of 11 patients with type 1 diabetes and 36 eyes of 18 healthy volunteers. OCTA images were evaluated for the presence of microvascular changes and measurement of foveal avascular zone (FAZ) area and vessel density (VD) measurements in the superficial capillary plexus (SCP) and deep capillary plexus (DCP) were performed. Results: OCTA revealed microvascular changes in 7 of 11 type 1 diabetes cases. There was no significant difference between the FAZ measurements between the diabetic group and the control group at the SCP and DCP levels (p=0.647, p=0.874, respectively). There was also no significant difference in VD measurements between the diabetic group and the control group (p> 0.05). Conclusion: In diabetic patients who are not clinically diagnosed with diabetic retinopathy, retinal microvascular damage may occur. OCTA is a rapid, noninvasive, and safe imaging modality that is useful in the recognition of microvascular findings that develop at an early stage.

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