Selçuk PARLAK, Muhammed Said BEŞLER, Utku Eren ÖZKAYA, Esra ÇIVGIN, Ebru Sengul PARLAK

COVID-19 HASTALARINDA YAŞ GRUPLARINA GÖRE TORAKS BT BULGULARI VE KLİNİK SONLANIM ARASINDAKİ İLİŞKİ

Amaç: COVID-19 hastalarında yaşın, toraks bilgisayarlı tomografi (BT) bulguları ve hastalık şiddeti üzerindekietkisini analiz etmek. Materyal ve Metot: Çalışma, 1 Nisan 2020-1 Haziran 2020 tarihleri arasındaki 367 COVID-19 hastasının toraksBT görüntülerini içeriyordu. Hastalar dört yaş grubuna ayrıldı: Grup A (≤19 yaş), grup B (20-39 yaş), grup C(40-59 yaş) ve grup D (≥60 yaş). BT'de lateralite, tutulan loblar, lezyon sayısı, lezyon tipleri ve lezyon dağılımıdeğerlendirildi ve karşılaştırıldı. Bulgular: Çalışma popülasyonu 367 hastadan (210 erkek, 157 kadın, ortalama yaş 47.50, aralık 12-92 yaş)oluşmaktaydı. Yaş grupları arasında cinsiyet farkı yoktu. Tüm yaş gruplarında en sık görülen BT bulgusu buzlucam opasitesiydi. Lezyon sayısının da daha fazla olduğu yaşlı hastalarda konsolidasyonlar, kaldırım taşımanzarası ve hava bronkogramları daha yaygındı. Yaşlı hastalarda üst loblar ve sağ orta lob daha sıketkilenmişti. Grup A ve B'de mortalite saptanmazken, grup C ve D’de yoğun bakım ihtiyacı ve ölüm oranlarıdaha yüksekti. ROC eğrisi analizi, kötü prognoz açısından 55 yaşın optimal kesim değeri olduğunu ortayakoydu. Sonuç: COVID-19 hastalarının toraks BT bulguları yaşa göre değişiklik göstermektedir. Bilateral, multiple veyaygın infiltrasyonlar, konsolidasyon, hava bronkogramı, kaldırım taşı manzarası ile üst lobların tutulumu veileri yaş kötü prognoz işareti olarak düşünülmelidir.

RELATIONSHIP BETWEEN THE CHEST CTCHARACTERISTICS AND CLINICAL OUTCOMES OFCOVID-19 PATIENTS BY AGE GROUPS

Objectives: To analyze the effect of age on chest computed tomography (CT) features and disease severity in COVID-19.Materials and Methods: The study included the chest CT images of 367 patients with COVID-19 between April 1, 2020, and June 1, 2020. The patients were divided into four age groups: Group A (≤19 years), group B (20-39 years), Group C (40-59 years), and Group D (≥60 years). On chest CT, laterality, involved lobes, number of lesions, lesion types, and lesion distribution were evaluated and compared.Results: The study population consisted of 367 patients (210 male and 157 female, mean age 47.50 years, range 12-92 years). There was no significant gender difference between the age groups. The most common CT finding in all age groups was ground-glass opacity. Consolidations, crazy-paving patterns, and air bronchograms were more common in elderly patients, in which the number of lesions was also higher. The upper lobes and the right middle lobe were affected more frequently in elderly patients. While no mortality was found in groups A and B, the rates of intensive care admission and mortality were higher in groups C and D. The ROC curve analysis revealed that 55 years of age was the optimal cut-off value to predict a worse outcome.Conclusion: The CT findings of COVID-19 patients vary in different age groups. Bilateral, multiple and diffuse infiltrations, consolidation, air bronchogram, and crazy-paving patterns, upper lobe involvement, and older age should be considered as an indicator for worse outcomes.

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