ÜRİNER SİSTEM ENFEKSİYONU OLAN ÇOCUKLARDA ÜST ÜRİNER SİSTEM ENFEKSİYONUNUN AYIRT EDİLMESİNDE CRP/ALBÜMİN ORANININ KULLANILMASI

Amaç: İdrar yolu enfeksiyonları (İYE) çocukluk çağında sık görülen enfeksiyonlardır. Enfeksiyonun seyri veklinik takibi lokalizasyonuna göre (alt ve üst) değişir. C-reaktif protein (CRP) albümin oranı (CAO), son yıllardakullanılan enflamatuar belirteçlerden biridir. Çalışmamızın amacı CAO kullanarak bu ayrımı araştırmaktır. Materyal ve Metot: Bu çalışma, İYE tanısı almış 95 çocuğun hasta dosyaları taranarak gerçekleştirildi. Hastalarenfeksiyon bölgesine göre üst İYE (Ü-İYE) ve alt İYE (A-İYE) olarak iki gruba ayrıldı. Hastaların laboratuvar vedemografik özellikleri hastane kayıtlarından elde edilmiş ve gruplar arasında karşılaştırılmıştır. Bulgular: CAR, Ü-İYE grubunda anlamlı olarak daha yüksekti (p % 97 özgüllüğü ve% 53 duyarlılığı olan> 12,65 idi (AUC= 0,864; % 95 güven aralığı CI: 0,792– 0,9363, LR: 24,40; p

USE OF CRP/ALBUMIN RATIO IN THEDIFFERENTIATION OF UPPER URINARY SYSTEMINFECTION IN CHILDREN WITH A URINARY SYSTEMINFECTION

Objectives: Urinary tract infections (UTI) are common infections in childhood. The course of infection and its clinical follow-up vary according to its localization (lower vs. upper). C-reactive protein (CRP) albumin ratio (CAR) is one of the inflammatory markers that have been used in recent years. The purpose of our study is to investigate this distinction by using CAR.Materials and Methods: This study was conducted by scanning the patient files of 95 children diagnosed with UTI. The patients were divided into two groups according to the infection site as upper UTI (UUTI) and lower UTI (LUTI). Laboratory and demographic features of the patients were obtained from the hospital records and compared between the groups.Results: CAR was significantly greater in the UUTI group (p12.65, which had a specificity of 97% and sensitivity of 53% (AUC = 0.864; 95% confidence interval CI: 0.792–0.9363, LR: 24.40; p < 0.001). In the multivariate logistic regression analysis, in which variables found to be significant in univariate analysis and correlated with UUTI were also taken, CAR (OR = 0.897, 95% CI: 0.838-0.960, p = 0.002) and absolute neutrophil count (OR = 0.182, 95% CI: 0.039 -0.841, p = 0.029) was still found to be significant.Conclusion: CAR is independently related to UUTI in UTI and may be useful to predict UUTI.

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